Rossella Benedetti

Rome, 00161, Italy

Last Updated: 09/26/2026

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Found 40 publications

Correction: Di Crosta et al. Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells. Biomedicines 2025, 13, 2279.

Correction: Di Crosta et al. Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells. Biomedicines 2025, 13, 2279.

Journal: Biomedicines

Published: April 15, 2026

HHV-6A Drives Epigenetic Reprogramming via an EZH2-SIRT1 Axis to Sustain Mutant p53 and Reshape Oncogenic Inflammatory Signaling.

HHV-6A Drives Epigenetic Reprogramming via an EZH2-SIRT1 Axis to Sustain Mutant p53 and Reshape Oncogenic Inflammatory Signaling.

Journal: Viruses

Published: February 24, 2026

The yin and yang interplay between HDAC6 and KDM1 regulates the lysosomal degradation of mutp53 in colon cancer cells undergoing TG-induced ER stress.

The yin and yang interplay between HDAC6 and KDM1 regulates the lysosomal degradation of mutp53 in colon cancer cells undergoing TG-induced ER stress.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: January 28, 2026

Acetylation promotes mutant (MUT) TP53-HSPA8 and HSPA8-BAG3 interactions, facilitating MUT TP53 lysosomal degradation preferentially via CASA.

Acetylation promotes mutant (MUT) TP53-HSPA8 and HSPA8-BAG3 interactions, facilitating MUT TP53 lysosomal degradation preferentially via CASA.

Journal: Autophagy

Published: October 16, 2025

Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cells.

Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cells.

Journal: Cell death discovery

Published: August 29, 2025

Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells.

Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells.

Journal: Biomedicines

Published: July 23, 2025

Targeting EZH2 in Cancer: Mechanisms, Pathways, and Therapeutic Potential.

Targeting EZH2 in Cancer: Mechanisms, Pathways, and Therapeutic Potential.

Journal: Molecules (Basel, Switzerland)

Published: November 14, 2024

Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.

Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.

Journal: Cell death discovery

Published: November 13, 2024

Post-Translational Modifications (PTMs) of mutp53 and Epigenetic Changes Induced by mutp53.

Post-Translational Modifications (PTMs) of mutp53 and Epigenetic Changes Induced by mutp53.

Journal: Biology

Published: June 13, 2024

EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?

EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?

Journal: Biochimica et biophysica acta. Gene regulatory mechanisms

Published: June 10, 2024

SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells.

SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells.

Journal: International journal of molecular sciences

Published: May 27, 2024

Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions.

Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions.

Journal: Biomolecules

Published: May 07, 2024

Showing 1-12 of 40

Last Updated: 09/26/2026