Roy Hanna

5415 Boul. L'Assomption
Montreal, QC H1T2M4, Canada

Last Updated: 09/26/2026

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Found 11 publications

BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication.

BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication.

Journal: The Journal of biological chemistry

Published: June 12, 2025

Epigenomic alterations and neural development anomalies in induced pluripotent stem cells from sporadic Alzheimer's disease.

Epigenomic alterations and neural development anomalies in induced pluripotent stem cells from sporadic Alzheimer's disease.

Journal: Development (Cambridge, England)

Published: May 02, 2025

Pharmaceutical inhibition of the Chk2 kinase mitigates cone photoreceptor degeneration in an iPSC model of Bardet-Biedl syndrome.

Pharmaceutical inhibition of the Chk2 kinase mitigates cone photoreceptor degeneration in an iPSC model of Bardet-Biedl syndrome.

Journal: iScience

Published: June 18, 2024

Molecular characterization and sub-retinal transplantation of hypoimmunogenic human retinal sheets in a minipig model of severe photoreceptor degeneration.

Molecular characterization and sub-retinal transplantation of hypoimmunogenic human retinal sheets in a minipig model of severe photoreceptor degeneration.

Journal: Development (Cambridge, England)

Published: May 22, 2024

Progression of swallowing dysfunction and associated complications of dysphagia in a cohort of patients with serial videofluoroscopic swallow examinations.

Progression of swallowing dysfunction and associated complications of dysphagia in a cohort of patients with serial videofluoroscopic swallow examinations.

Journal: The Journal of laryngology and otology

Published: June 10, 2021

G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease.

G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease.

Journal: Nature communications

Published: December 30, 2019

Deregulation of Neuro-Developmental Genes and Primary Cilium Cytoskeleton Anomalies in iPSC Retinal Sheets from Human Syndromic Ciliopathies.

Deregulation of Neuro-Developmental Genes and Primary Cilium Cytoskeleton Anomalies in iPSC Retinal Sheets from Human Syndromic Ciliopathies.

Journal: Stem cell reports

Published: July 08, 2019

Off-target effect of the BMI1 inhibitor PTC596 drives epithelial-mesenchymal transition in glioblastoma multiforme.

Off-target effect of the BMI1 inhibitor PTC596 drives epithelial-mesenchymal transition in glioblastoma multiforme.

Journal: NPJ precision oncology

Published: February 24, 2019

Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.

Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.

Journal: Scientific reports

Published: June 13, 2018

The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells.

The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells.

Journal: The Journal of biological chemistry

Published: April 29, 2015

Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors.

Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors.

Journal: Development (Cambridge, England)

Published: April 13, 2015

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Last Updated: 09/26/2026