Last Updated: 09/26/2026
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Found 6 publications
A randomized, double-blind, placebo- and positive-controlled crossover study of the effects of durlobactam on cardiac repolarization in healthy subjects.
Journal: Clinical and translational science
Published: December 18, 2020
A Phase 1 Randomized, Placebo-controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of Inactivated Streptococcus pneumoniae Whole-cell Vaccine in Adults.
Journal: The Pediatric infectious disease journal
Published: January 03, 2020
Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: October 08, 2013
Trametinib, a first-in-class oral MEK inhibitor mass balance study with limited enrollment of two male subjects with advanced cancers.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: August 27, 2013
Concomitant oral and intravenous pharmacokinetics of trametinib, a MEK inhibitor, in subjects with solid tumours.
Journal: British journal of clinical pharmacology
Published: June 11, 2013
Concomitant oral and intravenous pharmacokinetics of dabrafenib, a BRAF inhibitor, in patients with BRAF V600 mutation-positive solid tumors.
Journal: Journal of clinical pharmacology
Published: March 08, 2013
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Last Updated: 09/26/2026