Ruben Alcoceba-Hernandez

Pamplona, NC, Spain

Last Updated: 09/26/2026

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Found 45 publications

Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease.

Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease.

Journal: NPJ Parkinson's disease
Published: September 22, 2025

Evaluation of methods to increase the expression of cytokine-induced killer cell chemoattractant cytokines in pancreatic cancer.

Evaluation of methods to increase the expression of cytokine-induced killer cell chemoattractant cytokines in pancreatic cancer.

Journal: Gene therapy
Published: April 02, 2025

Characterization of brain transduction capability of a BBB-penetrant AAV vector in mice, rats and macaques reveals differences in expression profiles.

Characterization of brain transduction capability of a BBB-penetrant AAV vector in mice, rats and macaques reveals differences in expression profiles.

Journal: Gene therapy
Published: May 16, 2024

Engineering U1-Based Tetracycline-Inducible Riboswitches to Control Gene Expression in Mammals.

Engineering U1-Based Tetracycline-Inducible Riboswitches to Control Gene Expression in Mammals.

Journal: ACS nano
Published: November 16, 2023

Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome.

Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome.

Journal: Journal of molecular medicine (Berlin, Germany)
Published: May 05, 2023

Application of a split-Cre system for high-capacity adenoviral vector amplification.

Application of a split-Cre system for high-capacity adenoviral vector amplification.

Journal: Biotechnology journal
Published: May 05, 2022

Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma.

Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma.

Journal: Molecular therapy oncolytics
Published: April 04, 2022

Viral vector-mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome.

Viral vector-mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome.

Journal: The Journal of clinical investigation
Published: February 14, 2022

Preclinical model for phenotypic correction of dystrophic epidermolysis bullosa by in vivo CRISPR-Cas9 delivery using adenoviral vectors.

Preclinical model for phenotypic correction of dystrophic epidermolysis bullosa by in vivo CRISPR-Cas9 delivery using adenoviral vectors.

Journal: Molecular therapy. Methods & clinical development
Published: January 13, 2022

High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson's disease.

High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson's disease.

Journal: Molecular therapy. Methods & clinical development
Published: November 10, 2021

Broad virus inactivation using inorganic micro/nano-particulate materials.

Broad virus inactivation using inorganic micro/nano-particulate materials.

Journal: Materials today. Bio
Published: October 07, 2021

Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis.

Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis.

Journal: Molecular therapy. Methods & clinical development
Published: May 07, 2021
Showing 1-12 of 45

Last Updated: 09/26/2026