Rudolf Andrys

Hradec Kralove, KR 50003, Czech Republic

Last Updated: 09/26/2026

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Found 59 publications

Dual Inhibitors of p38α Mitogen-Activated Protein Kinase and Butyrylcholinesterase for the Modulation of Neuroinflammation and Cognitive Dysfunction.

Dual Inhibitors of p38α Mitogen-Activated Protein Kinase and Butyrylcholinesterase for the Modulation of Neuroinflammation and Cognitive Dysfunction.

Journal: Journal of medicinal chemistry

Published: May 06, 2026

Discovery of 1-(3-phenoxybenzyl)-4-(1-phenyl-1H-1,2,3-triazol-4-yl)piperidine analogues as potent and selective agonists of the human CC chemokine receptor 8.

Discovery of 1-(3-phenoxybenzyl)-4-(1-phenyl-1H-1,2,3-triazol-4-yl)piperidine analogues as potent and selective agonists of the human CC chemokine receptor 8.

Journal: European journal of medicinal chemistry

Published: April 28, 2026

Development of Novel 17β-HSD10 Inhibitors and Their Evaluation in an In Vitro Model of Alzheimer's Disease.

Development of Novel 17β-HSD10 Inhibitors and Their Evaluation in an In Vitro Model of Alzheimer's Disease.

Journal: ACS medicinal chemistry letters

Published: March 09, 2026

The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities.

The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities.

Journal: Bioorganic chemistry

Published: January 14, 2026

Derivatization agents for LC-MS analysis of amino acids: effects of core structure and functional groups.

Derivatization agents for LC-MS analysis of amino acids: effects of core structure and functional groups.

Journal: Analytical and bioanalytical chemistry

Published: November 23, 2025

In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects.

In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects.

Journal: Cancer cell international

Published: September 05, 2025

Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38α Mitogen-Activated Protein Kinase Inhibitors.

Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38α Mitogen-Activated Protein Kinase Inhibitors.

Journal: Journal of medicinal chemistry

Published: August 08, 2025

Transforming ureas into carbamates: From allosteric p38α MAPK ligands to dual BChE/p38α MAPK inhibitors.

Transforming ureas into carbamates: From allosteric p38α MAPK ligands to dual BChE/p38α MAPK inhibitors.

Journal: Bioorganic chemistry

Published: July 14, 2025

Small-Molecule Kinase Inhibitors Modulating Circadian Rhythms.

Small-Molecule Kinase Inhibitors Modulating Circadian Rhythms.

Journal: Medicinal research reviews

Published: June 10, 2025

Degradation behavior and environmental impacts of a hemp-containing "eco-friendly" compostable plastic in natural environments.

Degradation behavior and environmental impacts of a hemp-containing "eco-friendly" compostable plastic in natural environments.

Journal: Waste management (New York, N.Y.)

Published: May 12, 2025

Chitosan-based film-forming systems with cannabidiol: a novel topical strategy for antimicrobial therapy.

Chitosan-based film-forming systems with cannabidiol: a novel topical strategy for antimicrobial therapy.

Journal: International journal of pharmaceutics

Published: May 07, 2025

New insights into the 17β-hydroxysteroid dehydrogenase type 10 and amyloid-β 42 derived cytotoxicity relevant to Alzheimer's disease.

New insights into the 17β-hydroxysteroid dehydrogenase type 10 and amyloid-β 42 derived cytotoxicity relevant to Alzheimer's disease.

Journal: Alzheimer's research & therapy

Published: April 22, 2025

Showing 1-12 of 59

Last Updated: 09/26/2026