Ruenn C. Lai

1 Tai Seng Ave, #02-04 Tai Seng Exchange
Singapore, 536464, Singapore

Last Updated: 09/26/2026

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Found 44 publications

A phase 1, open-label study to determine safety and tolerability of the topical application of mesenchymal stem/stromal cell (MSC) exosome ointment to treat psoriasis in healthy volunteers.

A phase 1, open-label study to determine safety and tolerability of the topical application of mesenchymal stem/stromal cell (MSC) exosome ointment to treat psoriasis in healthy volunteers.

Journal: Cytotherapy

Published: August 25, 2024

Enhancing EV-cell communication through "External Modulation of Cell by EV" (EMCEV).

Enhancing EV-cell communication through "External Modulation of Cell by EV" (EMCEV).

Journal: Cytotherapy

Published: May 15, 2024

An Assessment of Administration Route on MSC-sEV Therapeutic Efficacy.

An Assessment of Administration Route on MSC-sEV Therapeutic Efficacy.

Journal: Biomolecules

Published: April 09, 2024

Standard Radio-Iodine Labeling Protocols Impaired the Functional Integrity of Mesenchymal Stem/Stromal Cell Exosomes.

Standard Radio-Iodine Labeling Protocols Impaired the Functional Integrity of Mesenchymal Stem/Stromal Cell Exosomes.

Journal: International journal of molecular sciences

Published: February 08, 2024

Therapeutic Efficacy of Mesenchymal Stem/Stromal Cell Small Extracellular Vesicles in Alleviating Arthritic Progression by Restoring Macrophage Balance.

Therapeutic Efficacy of Mesenchymal Stem/Stromal Cell Small Extracellular Vesicles in Alleviating Arthritic Progression by Restoring Macrophage Balance.

Journal: Biomolecules

Published: August 25, 2023

MSC-Derived Small Extracellular Vesicles Exert Cardioprotective Effect Through Reducing VLCFAs and Apoptosis in Human Cardiac Organoid IRI Model.

MSC-Derived Small Extracellular Vesicles Exert Cardioprotective Effect Through Reducing VLCFAs and Apoptosis in Human Cardiac Organoid IRI Model.

Journal: Stem cells (Dayton, Ohio)

Published: August 01, 2023

Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5'-Nucleotidase Activity.

Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5'-Nucleotidase Activity.

Journal: Pharmaceutics

Published: April 17, 2023

Mesenchymal Stem Cell Exosomes as Immunomodulatory Therapy for Corneal Scarring.

Mesenchymal Stem Cell Exosomes as Immunomodulatory Therapy for Corneal Scarring.

Journal: International journal of molecular sciences

Published: March 04, 2023

MSC-sEV Treatment Polarizes Pro-Fibrotic M2 Macrophages without Exacerbating Liver Fibrosis in NASH.

MSC-sEV Treatment Polarizes Pro-Fibrotic M2 Macrophages without Exacerbating Liver Fibrosis in NASH.

Journal: International journal of molecular sciences

Published: March 03, 2023

Mesenchymal stromal cell exosomes enhance dental pulp cell functions and promote pulp-dentin regeneration.

Mesenchymal stromal cell exosomes enhance dental pulp cell functions and promote pulp-dentin regeneration.

Journal: Biomaterials and biosystems

Published: February 26, 2023

A roadmap from research to clinical testing of mesenchymal stromal cell exosomes in the treatment of psoriasis.

A roadmap from research to clinical testing of mesenchymal stromal cell exosomes in the treatment of psoriasis.

Journal: Cytotherapy

Published: October 28, 2022

HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury.

HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury.

Journal: Cell death discovery

Published: July 12, 2022

Showing 1-12 of 44

Last Updated: 09/26/2026