Run-ling Wang

Tianjin Key Laboratory Of Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Tianjin, China

Last Updated: 09/26/2026

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Found 35 publications

Exploring the mechanism of C473D mutation on CDC25B causing weak binding affinity with CDK2/CyclinA by molecular dynamics study.

Exploring the mechanism of C473D mutation on CDC25B causing weak binding affinity with CDK2/CyclinA by molecular dynamics study.

Journal: Journal of biomolecular structure & dynamics

Published: January 19, 2023

Identification of the potential dual inhibitor of protein tyrosine phosphatase sigma and leukocyte common antigen-related phosphatase by virtual screen, molecular dynamic simulations and post-analysis.

Identification of the potential dual inhibitor of protein tyrosine phosphatase sigma and leukocyte common antigen-related phosphatase by virtual screen, molecular dynamic simulations and post-analysis.

Journal: Journal of biomolecular structure & dynamics

Published: December 18, 2019

Design potential selective inhibitors for human leukocyte common antigen-related (PTP-LAR) with fragment replace approach.

Design potential selective inhibitors for human leukocyte common antigen-related (PTP-LAR) with fragment replace approach.

Journal: Journal of biomolecular structure & dynamics

Published: December 03, 2019

Identification of novel inhibitor of protein tyrosine phosphatases delta: structure-based pharmacophore modeling, virtual screening, flexible docking, molecular dynamics simulation, and post-molecular dynamics analysis.

Identification of novel inhibitor of protein tyrosine phosphatases delta: structure-based pharmacophore modeling, virtual screening, flexible docking, molecular dynamics simulation, and post-molecular dynamics analysis.

Journal: Journal of biomolecular structure & dynamics

Published: October 19, 2019

Identification of potential leukocyte antigen-related protein (PTP-LAR) inhibitors through 3D QSAR pharmacophore-based virtual screening and molecular dynamics simulation.

Identification of potential leukocyte antigen-related protein (PTP-LAR) inhibitors through 3D QSAR pharmacophore-based virtual screening and molecular dynamics simulation.

Journal: Journal of biomolecular structure & dynamics

Published: October 08, 2019

Design, synthesis, biological evaluation and molecular dynamics studies of 4-thiazolinone derivatives as protein tyrosine phosphatase 1B (PTP1B) inhibitors.

Design, synthesis, biological evaluation and molecular dynamics studies of 4-thiazolinone derivatives as protein tyrosine phosphatase 1B (PTP1B) inhibitors.

Journal: Journal of biomolecular structure & dynamics

Published: September 07, 2019

Investigating the reason for loss-of-function of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) caused by Y279C mutation through molecular dynamics simulation.

Investigating the reason for loss-of-function of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) caused by Y279C mutation through molecular dynamics simulation.

Journal: Journal of biomolecular structure & dynamics

Published: July 02, 2019

Probing the acting mode and advantages of RMC-4550 as an Src-homology 2 domain-containing protein tyrosine phosphatase (SHP2) inhibitor at molecular level through molecular docking and molecular dynamics.

Probing the acting mode and advantages of RMC-4550 as an Src-homology 2 domain-containing protein tyrosine phosphatase (SHP2) inhibitor at molecular level through molecular docking and molecular dynamics.

Journal: Journal of biomolecular structure & dynamics

Published: May 03, 2019

Exploring the cause of the inhibitor 4AX attaching to binding site disrupting protein tyrosine phosphatase 4A1 trimerization by molecular dynamic simulation.

Exploring the cause of the inhibitor 4AX attaching to binding site disrupting protein tyrosine phosphatase 4A1 trimerization by molecular dynamic simulation.

Journal: Journal of biomolecular structure & dynamics

Published: January 22, 2019

Exploring the effect of inhibitor AKB-9778 on VE-PTP by molecular docking and molecular dynamics simulation.

Exploring the effect of inhibitor AKB-9778 on VE-PTP by molecular docking and molecular dynamics simulation.

Journal: Journal of cellular biochemistry

Published: December 20, 2018

Exploring the effect of E76K mutation on SHP2 cause gain-of-function activity by a molecular dynamics study.

Exploring the effect of E76K mutation on SHP2 cause gain-of-function activity by a molecular dynamics study.

Journal: Journal of cellular biochemistry

Published: April 20, 2018

Scaffold-based novel SHP2 allosteric inhibitors design using Receptor-Ligand pharmacophore model, virtual screening and molecular dynamics.

Scaffold-based novel SHP2 allosteric inhibitors design using Receptor-Ligand pharmacophore model, virtual screening and molecular dynamics.

Journal: Computational biology and chemistry

Published: November 29, 2017

Showing 1-12 of 35

Last Updated: 09/26/2026