Ruoyang H. Miao

Zhengzhou, 450052, China

Last Updated: 09/26/2026

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Found 14 publications

Identification of Tumor Hypoxia-Activated Degradation-Targeting Chimeras.

Identification of Tumor Hypoxia-Activated Degradation-Targeting Chimeras.

Journal: Journal of medicinal chemistry

Published: February 21, 2026

Catalyst-Free, Divergent Cysteine Modification via Indole Isocyanide Photochemistry.

Catalyst-Free, Divergent Cysteine Modification via Indole Isocyanide Photochemistry.

Journal: Angewandte Chemie (International ed. in English)

Published: November 06, 2025

Discovery of C2: A Novel Lead Compound for the Treatment of Gout and Hyperuricemia via Multi-Pathway Inhibition.

Discovery of C2: A Novel Lead Compound for the Treatment of Gout and Hyperuricemia via Multi-Pathway Inhibition.

Journal: Archiv der Pharmazie

Published: September 15, 2025

Optimization of novel TRPV1 antagonists bearing 1-((2,2-difluorobenzo[d][1,3] dioxol-5-yl) methyl) piperazine for pain management: Mechanistic insights into NLRP3 Inflammasome modulation.

Optimization of novel TRPV1 antagonists bearing 1-((2,2-difluorobenzo[d][1,3] dioxol-5-yl) methyl) piperazine for pain management: Mechanistic insights into NLRP3 Inflammasome modulation.

Journal: Bioorganic & medicinal chemistry

Published: August 26, 2025

Design, synthesis, and biological evaluation of 2, 6-di-substituted indole derivatives as METTL3 inhibitors.

Design, synthesis, and biological evaluation of 2, 6-di-substituted indole derivatives as METTL3 inhibitors.

Journal: European journal of medicinal chemistry

Published: May 12, 2025

Identification of novel 2, 6-Di-substituted Imidazo[1,2-a]pyridine derivatives as potent METTL3 inhibitors.

Identification of novel 2, 6-Di-substituted Imidazo[1,2-a]pyridine derivatives as potent METTL3 inhibitors.

Journal: Bioorganic chemistry

Published: May 12, 2025

Structure optimization of natural product piperine to obtain novel and potent analogs with anti-inflammation pain and urate-lowering effect.

Structure optimization of natural product piperine to obtain novel and potent analogs with anti-inflammation pain and urate-lowering effect.

Journal: European journal of medicinal chemistry

Published: February 14, 2025

Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer.

Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer.

Journal: Bioorganic & medicinal chemistry

Published: March 31, 2023

Design, synthesis and biological evaluation of the tumor hypoxia-activated PROTACs bearing caged CRBN E3 ligase ligands.

Design, synthesis and biological evaluation of the tumor hypoxia-activated PROTACs bearing caged CRBN E3 ligase ligands.

Journal: Bioorganic & medicinal chemistry

Published: January 18, 2023

Chemoproteomics reveals arctigenin as a phagophore-closure blocker via targeting ESCRT-I subunit VPS28.

Chemoproteomics reveals arctigenin as a phagophore-closure blocker via targeting ESCRT-I subunit VPS28.

Journal: Bioorganic chemistry

Published: December 26, 2022

Research progress and challenges of TRPV1 channel modulators as a prospective therapy for diabetic neuropathic pain.

Research progress and challenges of TRPV1 channel modulators as a prospective therapy for diabetic neuropathic pain.

Journal: European journal of medicinal chemistry

Published: August 23, 2022

Design, synthesis and biological evaluation of novel tumor hypoxia-activated EGFR tyrosine kinase inhibitors.

Design, synthesis and biological evaluation of novel tumor hypoxia-activated EGFR tyrosine kinase inhibitors.

Journal: Bioorganic chemistry

Published: July 25, 2022

Showing 1-12 of 14

Last Updated: 09/26/2026