Rurika Oka

Utrecht, UT 3584CS, Netherlands

Last Updated: 09/26/2026

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Found 27 publications

DNA mismatch repair controls the mutagenicity of Polymerase ζ-dependent translesion synthesis at methylated guanines.

DNA mismatch repair controls the mutagenicity of Polymerase ζ-dependent translesion synthesis at methylated guanines.

Journal: DNA repair

Published: May 05, 2024

Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids.

Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids.

Journal: Nature cancer

Published: December 21, 2022

Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms.

Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms.

Journal: Cancer discovery

Published: January 28, 2022

MutationalPatterns: the one stop shop for the analysis of mutational processes.

MutationalPatterns: the one stop shop for the analysis of mutational processes.

Journal: BMC genomics

Published: November 08, 2021

Mutation signatures of pediatric acute myeloid leukemia and normal blood progenitors associated with differential patient outcomes.

Mutation signatures of pediatric acute myeloid leukemia and normal blood progenitors associated with differential patient outcomes.

Journal: Blood cancer discovery

Published: October 13, 2021

Molecular characterization of Barrett's esophagus at single-cell resolution.

Molecular characterization of Barrett's esophagus at single-cell resolution.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: October 05, 2021

Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo.

Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo.

Journal: iScience

Published: October 01, 2021

Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.

Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 22, 2021

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.

Journal: Nature biotechnology

Published: February 05, 2021

Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients.

Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients.

Journal: Cell stem cell

Published: January 11, 2021

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids.

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids.

Journal: Life science alliance

Published: October 19, 2020

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer.

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer.

Journal: Cell stem cell

Published: June 02, 2020

Showing 1-12 of 27

Last Updated: 09/26/2026