Ruth R. French

Tremona Road
Southampton, ENG SO166YD, United Kingdom

Last Updated: 09/26/2026

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Found 18 publications

HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy.

HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy.

Journal: Journal of experimental & clinical cancer research : CR

Published: October 04, 2021

TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity.

TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity.

Journal: Communications biology

Published: February 05, 2021

On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.

On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.

Journal: Communications biology

Published: September 23, 2020

Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity.

Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity.

Journal: Cancer cell

Published: October 28, 2019

Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies.

Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies.

Journal: Cancer cell

Published: October 24, 2017

Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking.

Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking.

Journal: Scientific reports

Published: August 04, 2017

Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity.

Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity.

Journal: British journal of haematology

Published: November 04, 2016

OX40+ Regulatory T Cells in Cutaneous Squamous Cell Carcinoma Suppress Effector T-Cell Responses and Associate with Metastatic Potential.

OX40+ Regulatory T Cells in Cutaneous Squamous Cell Carcinoma Suppress Effector T-Cell Responses and Associate with Metastatic Potential.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: October 27, 2015

Anti-mouse FcγRIV antibody 9E9 also blocks FcγRIII in vivo.

Anti-mouse FcγRIV antibody 9E9 also blocks FcγRIII in vivo.

Journal: Blood

Published: October 24, 2015

Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies.

Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies.

Journal: Blood

Published: January 30, 2015

Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors.

Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: December 04, 2014

Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412.

Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412.

Journal: Blood

Published: November 15, 2014

Showing 1-12 of 18

Last Updated: 09/26/2026