Ryan O. Dowling

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 20 publications

Exploration of body mass index and circulating metabolic factors as predictors of metformin benefit in the Canadian Cancer Trials Group MA.32.

Exploration of body mass index and circulating metabolic factors as predictors of metformin benefit in the Canadian Cancer Trials Group MA.32.

Journal: JNCI cancer spectrum

Published: December 17, 2025

Insulin receptor loss impairs mammary tumorigenesis in mice.

Insulin receptor loss impairs mammary tumorigenesis in mice.

Journal: Cell reports

Published: September 30, 2022

Cancer Antigen 15-3/Mucin 1 Levels in CCTG MA.32: A Breast Cancer Randomized Trial of Metformin vs Placebo.

Cancer Antigen 15-3/Mucin 1 Levels in CCTG MA.32: A Breast Cancer Randomized Trial of Metformin vs Placebo.

Journal: JNCI cancer spectrum

Published: April 14, 2021

Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial.

Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial.

Journal: NPJ breast cancer

Published: December 21, 2020

The Effect of Metformin vs Placebo on Sex Hormones in Canadian Cancer Trials Group MA.32.

The Effect of Metformin vs Placebo on Sex Hormones in Canadian Cancer Trials Group MA.32.

Journal: Journal of the National Cancer Institute

Published: March 02, 2020

PTEN Nuclear Functions.

PTEN Nuclear Functions.

Journal: Cold Spring Harbor perspectives in medicine

Published: November 13, 2019

Metformin and Exercise in Cancer: Better Together.

Metformin and Exercise in Cancer: Better Together.

Journal: JNCI cancer spectrum

Published: November 01, 2019

A phase II randomized clinical trial of the effect of metformin versus placebo on progression-free survival in women with metastatic breast cancer receiving standard chemotherapy.

A phase II randomized clinical trial of the effect of metformin versus placebo on progression-free survival in women with metastatic breast cancer receiving standard chemotherapy.

Journal: Breast (Edinburgh, Scotland)

Published: June 26, 2019

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations.

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations.

Journal: JNCI cancer spectrum

Published: May 15, 2019

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions.

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions.

Journal: JNCI cancer spectrum

Published: May 15, 2019

Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study.

Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: September 28, 2018

Association of Metabolic, Inflammatory, and Tumor Markers With Circulating Tumor Cells in Metastatic Breast Cancer.

Association of Metabolic, Inflammatory, and Tumor Markers With Circulating Tumor Cells in Metastatic Breast Cancer.

Journal: JNCI cancer spectrum

Published: March 28, 2018

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Last Updated: 09/26/2026