Ryoko Takasawa

Noda, 2788510, Japan

Last Updated: 09/26/2026

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Found 22 publications

Caffeic acid phenethyl ester derivatives inhibit glyoxalase I activity and induce cell death in cultured cancer cell lines.

Caffeic acid phenethyl ester derivatives inhibit glyoxalase I activity and induce cell death in cultured cancer cell lines.

Journal: Bioorganic & medicinal chemistry letters

Published: June 22, 2026

Plakevulin A induces apoptosis and suppresses IL-6-induced STAT3 activation in HL60 cells.

Plakevulin A induces apoptosis and suppresses IL-6-induced STAT3 activation in HL60 cells.

Journal: Bioorganic & medicinal chemistry letters

Published: April 01, 2024

The PKM2 inhibitor shikonin enhances piceatannol-induced apoptosis of glyoxalase I-dependent cancer cells.

The PKM2 inhibitor shikonin enhances piceatannol-induced apoptosis of glyoxalase I-dependent cancer cells.

Journal: Genes to cells : devoted to molecular & cellular mechanisms

Published: June 20, 2023

Triphenylbismuth dichloride inhibits human glyoxalase I and induces cytotoxicity in cultured cancer cell lines.

Triphenylbismuth dichloride inhibits human glyoxalase I and induces cytotoxicity in cultured cancer cell lines.

Journal: The Journal of toxicological sciences

Published: November 30, 2022

Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference.

Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference.

Journal: FEBS letters

Published: February 11, 2022

Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-β1: Induction of Cystathionine γ-Lyase and Cystathionine β-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.

Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-β1: Induction of Cystathionine γ-Lyase and Cystathionine β-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.

Journal: International journal of molecular sciences

Published: September 28, 2021

GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.

GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.

Journal: Anticancer research

Published: September 11, 2021

Sodium trisulfide, a sulfane sulfur donor, stimulates bovine aortic endothelial cell proliferation in culture.

Sodium trisulfide, a sulfane sulfur donor, stimulates bovine aortic endothelial cell proliferation in culture.

Journal: The Journal of toxicological sciences

Published: July 01, 2021

β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells.

β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells.

Journal: Medicines (Basel, Switzerland)

Published: May 12, 2021

Addition of hydrophobic side chains improve the apoptosis inducibility of the human glyoxalase I inhibitor, TLSC702.

Addition of hydrophobic side chains improve the apoptosis inducibility of the human glyoxalase I inhibitor, TLSC702.

Journal: Bioorganic & medicinal chemistry letters

Published: October 12, 2020

Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer.

Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer.

Journal: Oncology letters

Published: September 02, 2020

Antinociceptive activity of the novel RAGE inhibitor, papaverine, in a mouse model of chronic inflammatory pain.

Antinociceptive activity of the novel RAGE inhibitor, papaverine, in a mouse model of chronic inflammatory pain.

Journal: Synapse (New York, N.Y.)

Published: June 23, 2020

Showing 1-12 of 22

Last Updated: 09/26/2026