Ryosuke Fukuda

6691330, Japan

Last Updated: 09/26/2026

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Found 16 publications

Antisense oligonucleotide targeting the E3 ligase RFFL potentiates CFTR modulator efficacy in CF primary bronchial epithelial cells.

Antisense oligonucleotide targeting the E3 ligase RFFL potentiates CFTR modulator efficacy in CF primary bronchial epithelial cells.

Journal: Molecular therapy. Nucleic acids

Published: May 30, 2025

Enhanced CFTR modulator efficacy in ΔF508 CFTR mouse organoids by ablation of RFFL ubiquitin ligase.

Enhanced CFTR modulator efficacy in ΔF508 CFTR mouse organoids by ablation of RFFL ubiquitin ligase.

Journal: Biochemical and biophysical research communications

Published: July 15, 2024

UBE3C Facilitates the ER-Associated and Peripheral Degradation of Misfolded CFTR.

UBE3C Facilitates the ER-Associated and Peripheral Degradation of Misfolded CFTR.

Journal: Cells

Published: November 13, 2023

Perturbation of EPHA2 and EFNA1 trans binding amplifies inflammatory response in airway epithelial cells.

Perturbation of EPHA2 and EFNA1 trans binding amplifies inflammatory response in airway epithelial cells.

Journal: iScience

Published: November 07, 2023

HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains.

HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains.

Journal: The Journal of cell biology

Published: August 01, 2023

Identification of α-Tocopherol succinate as an RFFL-substrate interaction inhibitor inducing peripheral CFTR stabilization and apoptosis.

Identification of α-Tocopherol succinate as an RFFL-substrate interaction inhibitor inducing peripheral CFTR stabilization and apoptosis.

Journal: Biochemical pharmacology

Published: May 26, 2023

The multiple ubiquitination mechanisms in CFTR peripheral quality control.

The multiple ubiquitination mechanisms in CFTR peripheral quality control.

Journal: Biochemical Society transactions

Published: March 07, 2023

The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure.

The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure.

Journal: International journal of molecular sciences

Published: December 20, 2022

The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC).

The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC).

Journal: Frontiers in molecular biosciences

Published: December 21, 2021

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis.

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 03, 2020

ELISA Based Protein Ubiquitylation Measurement.

ELISA Based Protein Ubiquitylation Measurement.

Journal: Bio-protocol

Published: September 22, 2019

The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors.

The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors.

Journal: Journal of cell science

Published: November 19, 2018

Showing 1-12 of 16

Last Updated: 09/26/2026