Ryuichi Ohgaki

Osaka, 5650871, Japan

Last Updated: 09/26/2026

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Found 43 publications

L-type amino acid transporter 1 deficiency delays intestinal tissue repair in dextran sulfate sodium-induced colitis.

L-type amino acid transporter 1 deficiency delays intestinal tissue repair in dextran sulfate sodium-induced colitis.

Journal: International immunopharmacology
Published: April 24, 2025

Sustained reductions in valine and isoleucine mediate anti-cancer pharmacological effects of inhibiting amino acid transporter LAT1 in cancer cells.

Sustained reductions in valine and isoleucine mediate anti-cancer pharmacological effects of inhibiting amino acid transporter LAT1 in cancer cells.

Journal: Cancer & metabolism
Published: January 29, 2025

The role of LAT1 in AOM/DSS-induced colorectal tumorigenesis.

The role of LAT1 in AOM/DSS-induced colorectal tumorigenesis.

Journal: Biochemical and biophysical research communications
Published: November 14, 2024

Pharmacological and structural insights into nanvuranlat, a selective LAT1 (SLC7A5) inhibitor, and its N-acetyl metabolite with implications for cancer therapy.

Pharmacological and structural insights into nanvuranlat, a selective LAT1 (SLC7A5) inhibitor, and its N-acetyl metabolite with implications for cancer therapy.

Journal: Scientific reports
Published: November 02, 2024

Amino acid transporter LAT1 is expressed on cancer cell-derived exosomes with potential as a diagnostic and prognostic biomarker.

Amino acid transporter LAT1 is expressed on cancer cell-derived exosomes with potential as a diagnostic and prognostic biomarker.

Journal: Scientific reports
Published: July 12, 2024

LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia.

LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia.

Journal: Scientific reports
Published: January 26, 2024

Structural basis of anticancer drug recognition and amino acid transport by LAT1.

Structural basis of anticancer drug recognition and amino acid transport by LAT1.

Journal: Nature communications
Published: January 05, 2024

Structure-activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1).

Structure-activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1).

Journal: Scientific reports
Published: December 30, 2023

Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells.

Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells.

Journal: Journal of pharmacological sciences
Published: December 19, 2023

Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation.

Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation.

Journal: Journal of pharmacological sciences
Published: December 14, 2023

Identification of tumor-suppressive miRNAs that target amino acid transporter LAT1 and exhibit anti-proliferative effects on cholangiocarcinoma cells.

Identification of tumor-suppressive miRNAs that target amino acid transporter LAT1 and exhibit anti-proliferative effects on cholangiocarcinoma cells.

Journal: Journal of pharmacological sciences
Published: December 04, 2023

Evaluation of LAT1 Expression in Patients With Lung Cancer and Mediastinal Tumors: 18F-FBPA PET Study With Immunohistological Comparison.

Evaluation of LAT1 Expression in Patients With Lung Cancer and Mediastinal Tumors: 18F-FBPA PET Study With Immunohistological Comparison.

Journal: Clinical nuclear medicine
Published: September 08, 2023
Showing 1-12 of 43

Last Updated: 09/26/2026