Saadia A. Karim

Garscube Estate
Glasgow, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 34 publications

Engineered cyclic peptide targeting ITGA5 disrupts tumor-stroma interaction to overcome desmoplasia and resistance in pancreatic ductal adenocarcinoma.

Engineered cyclic peptide targeting ITGA5 disrupts tumor-stroma interaction to overcome desmoplasia and resistance in pancreatic ductal adenocarcinoma.

Journal: Acta pharmaceutica Sinica. B

Published: February 25, 2025

A precision image-guided model of stereotactic ablative radiotherapy for hepatocellular carcinoma.

A precision image-guided model of stereotactic ablative radiotherapy for hepatocellular carcinoma.

Journal: Disease models & mechanisms

Published: January 24, 2025

Targeting PIKfyve-driven lipid metabolism in pancreatic cancer.

Targeting PIKfyve-driven lipid metabolism in pancreatic cancer.

Journal: Nature

Published: March 12, 2024

Targeted irradiation in an autochthonous mouse model of pancreatic cancer.

Targeted irradiation in an autochthonous mouse model of pancreatic cancer.

Journal: Disease models & mechanisms

Published: September 08, 2023

Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.

Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.

Journal: Journal for immunotherapy of cancer

Published: July 16, 2023

Optimisation of Sample Preparation from Primary Mouse Tissue to Maintain RNA Integrity for Methods Examining Translational Control.

Optimisation of Sample Preparation from Primary Mouse Tissue to Maintain RNA Integrity for Methods Examining Translational Control.

Journal: Cancers

Published: June 09, 2023

Correction: Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1.

Correction: Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1.

Journal: Oncogene

Published: January 20, 2023

Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1.

Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1.

Journal: Oncogene

Published: July 10, 2022

Loss of Cxcr2 in Myeloid Cells Promotes Tumour Progression and T Cell Infiltration in Invasive Bladder Cancer.

Loss of Cxcr2 in Myeloid Cells Promotes Tumour Progression and T Cell Infiltration in Invasive Bladder Cancer.

Journal: Bladder cancer (Amsterdam, Netherlands)

Published: December 07, 2021

Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.

Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.

Journal: Nature cancer

Published: March 19, 2021

Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade.

Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade.

Journal: Nature communications

Published: November 27, 2020

Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.

Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.

Journal: Cancer cell

Published: July 28, 2020

Showing 1-12 of 34

Last Updated: 09/26/2026