Sabine Wittmann
Erlangen, BY, Germany
Last Updated: 09/26/2026
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Found 17 publications
Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney.
Journal: Journal of the American Society of Nephrology : JASN
Published: March 25, 2024
A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements.
Journal: Frontiers in immunology
Published: February 17, 2023
Nsp16 shields SARS-CoV-2 from efficient MDA5 sensing and IFIT1-mediated restriction.
Journal: EMBO reports
Published: June 24, 2022
Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases.
Journal: The EMBO journal
Published: May 08, 2022
Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit.
Journal: The Journal of biological chemistry
Published: December 23, 2021
Human TRIM5α senses and restricts LINE-1 elements.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 12, 2020
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.
Journal: PLoS pathogens
Published: February 06, 2020
IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.
IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.
Journal: Cell host & microbe
Published: October 24, 2018
A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1.
Journal: Nature microbiology
Published: August 28, 2018
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.
Journal: Mobile DNA
Published: November 02, 2017
Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.
Journal: Retrovirology
Published: October 19, 2015
Last Updated: 09/26/2026