Sai Zhang

Qingdao, 266071, China

Last Updated: 09/26/2026

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Found 16 publications

Discovery of an Androgen Receptor Degrader Featuring a Pyridazinyl Glutarimide CRBN-Binding Motif for Transdermal Treatment of Androgenetic Alopecia.

Discovery of an Androgen Receptor Degrader Featuring a Pyridazinyl Glutarimide CRBN-Binding Motif for Transdermal Treatment of Androgenetic Alopecia.

Journal: Journal of medicinal chemistry
Published: May 29, 2026

Preserving the UFMylation-cilium axis mitigates blue light-induced retinal degeneration.

Preserving the UFMylation-cilium axis mitigates blue light-induced retinal degeneration.

Journal: Journal of molecular cell biology
Published: March 12, 2026

ZJK-807: A Selective PROTAC Degrader of KRASG12D Overcoming Resistance in Pancreatic Cancer.

ZJK-807: A Selective PROTAC Degrader of KRASG12D Overcoming Resistance in Pancreatic Cancer.

Journal: Journal of medicinal chemistry
Published: September 25, 2025

Discovery of LYA914, An Orally Bioavailable PROTAC Degrader Targeting the DNA Binding Domain of the Androgen Receptor for the Treatment of CRPC.

Discovery of LYA914, An Orally Bioavailable PROTAC Degrader Targeting the DNA Binding Domain of the Androgen Receptor for the Treatment of CRPC.

Journal: Journal of medicinal chemistry
Published: July 28, 2025

Rational Design of Dual Degraders by Incorporating Molecular Glue Structural Features into PROTAC Degraders.

Rational Design of Dual Degraders by Incorporating Molecular Glue Structural Features into PROTAC Degraders.

Journal: Journal of medicinal chemistry
Published: May 09, 2025

PSMA-Guided PROTAC Degraders for Tumor-Specific Protein Degradation in Prostate Cancer.

PSMA-Guided PROTAC Degraders for Tumor-Specific Protein Degradation in Prostate Cancer.

Journal: Journal of medicinal chemistry
Published: May 02, 2025

Restoration of N-glycosylation via leucine-activated leucyl-tRNA synthetase 1 overcomes chemoresistance in intrahepatic cholangiocarcinoma.

Restoration of N-glycosylation via leucine-activated leucyl-tRNA synthetase 1 overcomes chemoresistance in intrahepatic cholangiocarcinoma.

Journal: Journal of hepatology
Published: December 18, 2024

Ginkgolic acid inhibits CD8+ T cell activation and induces ferroptosis by lactate dehydrogenase A to exert immunosuppressive effect.

Ginkgolic acid inhibits CD8+ T cell activation and induces ferroptosis by lactate dehydrogenase A to exert immunosuppressive effect.

Journal: Journal of pharmaceutical analysis
Published: October 13, 2024

Targeted degradation of VEGF with bispecific aptamer-based LYTACs ameliorates pathological retinal angiogenesis.

Targeted degradation of VEGF with bispecific aptamer-based LYTACs ameliorates pathological retinal angiogenesis.

Journal: Theranostics
Published: May 15, 2024

KIF11 UFMylation Maintains Photoreceptor Cilium Integrity and Retinal Homeostasis.

KIF11 UFMylation Maintains Photoreceptor Cilium Integrity and Retinal Homeostasis.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: January 16, 2024

Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of Prostate Cancer.

Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of Prostate Cancer.

Journal: Journal of medicinal chemistry
Published: August 09, 2023

Ginkgolic acid inhibits the expression of SAE1 and induces ferroptosis to exert an anti-hepatic fibrosis effect.

Ginkgolic acid inhibits the expression of SAE1 and induces ferroptosis to exert an anti-hepatic fibrosis effect.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Published: July 28, 2023
Showing 1-12 of 16

Last Updated: 09/26/2026