Salvatore Guccione

Catania, 95125, Italy

Last Updated: 09/26/2026

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Found 29 publications

(±)-2-Cyclohexyl-5-methoxy-2H-chromene, a Synthetic 5-Methoxyflavone Derivative, Is a Selective DNA Polymerase-β Inhibitor with Neuroprotective Activity against β-Amyloid Toxicity.

(±)-2-Cyclohexyl-5-methoxy-2H-chromene, a Synthetic 5-Methoxyflavone Derivative, Is a Selective DNA Polymerase-β Inhibitor with Neuroprotective Activity against β-Amyloid Toxicity.

Journal: ACS chemical neuroscience

Published: December 10, 2025

Modulatory Effect of Natural Antioxidants on Tissue Transglutaminase Levels in Olfactory Ensheathing Cells Exposed to Amyloid-β: Integrated Biochemical and Computational Analysis.

Modulatory Effect of Natural Antioxidants on Tissue Transglutaminase Levels in Olfactory Ensheathing Cells Exposed to Amyloid-β: Integrated Biochemical and Computational Analysis.

Journal: BioFactors (Oxford, England)

Published: December 04, 2025

Modelling-filtered drug repurposing and first-in-protein SPR validation of histone deacetylase 4 inhibitors for Ataxia-telangiectasia.

Modelling-filtered drug repurposing and first-in-protein SPR validation of histone deacetylase 4 inhibitors for Ataxia-telangiectasia.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: August 19, 2025

Recent Applications of In Silico Approaches for Studying Receptor Mutations Associated with Human Pathologies.

Recent Applications of In Silico Approaches for Studying Receptor Mutations Associated with Human Pathologies.

Journal: Molecules (Basel, Switzerland)

Published: September 10, 2024

Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy.

Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: October 03, 2022

Routes to Reduce the Time and Failing in Drug Development.

Routes to Reduce the Time and Failing in Drug Development.

Journal: Current pharmaceutical design

Published: December 28, 2020

Parameters for Irreversible Inactivation of Monoamine Oxidase.

Parameters for Irreversible Inactivation of Monoamine Oxidase.

Journal: Molecules (Basel, Switzerland)

Published: November 20, 2020

Pharmacological properties and biochemical mechanisms of μ-opioid receptor ligands might be due to different binding poses: MD studies.

Pharmacological properties and biochemical mechanisms of μ-opioid receptor ligands might be due to different binding poses: MD studies.

Journal: Future medicinal chemistry

Published: September 25, 2020

Quantum Chemical and Molecular Dynamics Studies of MUC1 Calix[4,8]arene Scaffold Based Anticancer Vaccine Candidates.

Quantum Chemical and Molecular Dynamics Studies of MUC1 Calix[4,8]arene Scaffold Based Anticancer Vaccine Candidates.

Journal: Journal of chemical information and modeling

Published: August 21, 2020

Peptidomimetics in Silico.

Peptidomimetics in Silico.

Journal: Molecular informatics

Published: April 14, 2020

Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors.

Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors.

Journal: Future medicinal chemistry

Published: April 13, 2019

Exploring the Biological Activity of a Library of 1,2,5-Oxadiazole Derivatives Endowed With Antiproliferative Activity.

Exploring the Biological Activity of a Library of 1,2,5-Oxadiazole Derivatives Endowed With Antiproliferative Activity.

Journal: Anticancer research

Published: November 08, 2018

Showing 1-12 of 29

Last Updated: 09/26/2026