Salvatore Pacifico

Via Luigi Borsari 46
Ferrara, 44121, Italy

Last Updated: 09/26/2026

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Found 59 publications

Design of New Potent, Selective, and Long-Acting NOP Receptor Agonists through Multiple Sequential d-Amino Acid Substitutions of [Arg14 Lys15]N/OFQ(1-15)-NH2.

Design of New Potent, Selective, and Long-Acting NOP Receptor Agonists through Multiple Sequential d-Amino Acid Substitutions of [Arg14 Lys15]N/OFQ(1-15)-NH2.

Journal: Journal of medicinal chemistry

Published: July 23, 2026

Not Quite Folded: Challenges in Predicting the hNPS-hNPSR-Ile107 Complex With AlphaFold2 Multimer.

Not Quite Folded: Challenges in Predicting the hNPS-hNPSR-Ile107 Complex With AlphaFold2 Multimer.

Journal: ChemMedChem

Published: May 26, 2026

Synthesis and Pharmacological Characterization of Nociceptin/Orphanin FQ Dimeric Ligands.

Synthesis and Pharmacological Characterization of Nociceptin/Orphanin FQ Dimeric Ligands.

Journal: Journal of medicinal chemistry

Published: November 04, 2025

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits.

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits.

Journal: British journal of pharmacology

Published: September 03, 2025

Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors.

Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: May 21, 2025

Sex differences in response to NLRP3 inflammasome blockage in a mouse migraine model: A genetic and pharmacological study.

Sex differences in response to NLRP3 inflammasome blockage in a mouse migraine model: A genetic and pharmacological study.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: April 29, 2025

Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics.

Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics.

Journal: European journal of medicinal chemistry

Published: April 22, 2025

In vitro pharmacological evaluation of the novel NOP receptor partial agonist sunobinop.

In vitro pharmacological evaluation of the novel NOP receptor partial agonist sunobinop.

Journal: Biochemical pharmacology

Published: March 28, 2025

FAP inhibitors: are we really using the best method to evaluate the residence time?

FAP inhibitors: are we really using the best method to evaluate the residence time?

Journal: European journal of nuclear medicine and molecular imaging

Published: February 25, 2025

Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo.

Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo.

Journal: European journal of medicinal chemistry

Published: February 20, 2025

Probing non-peptide agonists binding at the human nociceptin/orphanin FQ receptor: a molecular modelling study.

Probing non-peptide agonists binding at the human nociceptin/orphanin FQ receptor: a molecular modelling study.

Journal: RSC medicinal chemistry

Published: September 24, 2024

Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications.

Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications.

Journal: EJNMMI radiopharmacy and chemistry

Published: February 12, 2024

Showing 1-12 of 59

Last Updated: 09/26/2026