Samah El Ghamrasni

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 15 publications

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

Journal: Nucleic acids research
Published: May 09, 2023

Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality.

Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality.

Journal: Cancer research
Published: September 19, 2022

The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations.

The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations.

Journal: Science advances
Published: September 07, 2022

Author Correction: Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.

Author Correction: Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.

Journal: Nature communications
Published: July 27, 2022

IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.

IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.

Journal: Cancer cell
Published: February 24, 2022

Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer.

Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer.

Journal: Molecular cancer research : MCR
Published: June 17, 2021

Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.

Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.

Journal: Nature communications
Published: October 09, 2020

Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.

Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.

Journal: Nature communications
Published: October 06, 2020

RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.

RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.

Journal: The Journal of clinical investigation
Published: May 29, 2020

Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor.

Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor.

Journal: Genome medicine
Published: August 28, 2019

RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.

RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.

Journal: Nature communications
Published: October 04, 2015

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: December 11, 2013
Showing 1-12 of 15

Last Updated: 09/26/2026