Samantha Littler

555 Wilmslow Road
Manchester, ENG M204GJ, United Kingdom

Last Updated: 09/26/2026

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Found 9 publications

Targeting SUMOylation in ovarian cancer: Sensitivity, resistance, and the role of MYC.

Targeting SUMOylation in ovarian cancer: Sensitivity, resistance, and the role of MYC.

Journal: iScience
Published: November 29, 2024

Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer.

Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer.

Journal: Cell reports. Medicine
Published: October 25, 2024

Intrinsic PARG inhibitor sensitivity is mimicked by TIMELESS haploinsufficiency and rescued by nucleoside supplementation.

Intrinsic PARG inhibitor sensitivity is mimicked by TIMELESS haploinsufficiency and rescued by nucleoside supplementation.

Journal: NAR cancer
Published: February 28, 2024

Exploiting a living biobank to delineate mechanisms underlying disease-specific chromosome instability.

Exploiting a living biobank to delineate mechanisms underlying disease-specific chromosome instability.

Journal: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology
Published: April 25, 2023

Oncogenic MYC amplifies mitotic perturbations.

Oncogenic MYC amplifies mitotic perturbations.

Journal: Open biology
Published: August 29, 2019

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.

Journal: Nature communications
Published: November 21, 2018

DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors.

DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors.

Journal: Cancer cell
Published: September 20, 2018

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α.

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α.

Journal: Cell reports
Published: March 13, 2018

MYC Is a Major Determinant of Mitotic Cell Fate.

MYC Is a Major Determinant of Mitotic Cell Fate.

Journal: Cancer cell
Published: October 10, 2014
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Last Updated: 09/26/2026