Samuel G. Lessard

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 25 publications

The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications.

The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications.

Journal: bioRxiv : the preprint server for biology

Published: May 07, 2026

The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications.

The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications.

Journal: bioRxiv : the preprint server for biology

Published: May 07, 2026

Selective AMPKβ1 activation induces fetal hemoglobin in human erythroid cells and sickle cell mice via the noncanonical NRF2 pathway.

Selective AMPKβ1 activation induces fetal hemoglobin in human erythroid cells and sickle cell mice via the noncanonical NRF2 pathway.

Journal: Science advances

Published: November 19, 2025

Building a human genetic data lake to scale up insights for drug discovery.

Building a human genetic data lake to scale up insights for drug discovery.

Journal: Drug discovery today

Published: February 19, 2025

Genetic liability to psoriasis predicts severe disease outcomes.

Genetic liability to psoriasis predicts severe disease outcomes.

Journal: Genome medicine

Published: July 07, 2024

Genetic analyses of inflammatory polyneuropathy and chronic inflammatory demyelinating polyradiculoneuropathy identified candidate genes.

Genetic analyses of inflammatory polyneuropathy and chronic inflammatory demyelinating polyradiculoneuropathy identified candidate genes.

Journal: HGG advances

Published: January 10, 2024

Genome-wide association study analysis of disease severity in Acne reveals novel biological insights.

Genome-wide association study analysis of disease severity in Acne reveals novel biological insights.

Journal: medRxiv : the preprint server for health sciences

Published: November 28, 2023

Leveraging large-scale multi-omics evidences to identify therapeutic targets from genome-wide association studies.

Leveraging large-scale multi-omics evidences to identify therapeutic targets from genome-wide association studies.

Journal: BMC genomics

Published: November 15, 2023

Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease.

Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease.

Journal: Scientific reports

Published: November 13, 2023

SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.

SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.

Journal: Blood advances

Published: August 04, 2022

Genome-Wide Association Study and Gene-Based Analysis of Participants With Hemophilia A and Inhibitors in the My Life, Our Future Research Repository.

Genome-Wide Association Study and Gene-Based Analysis of Participants With Hemophilia A and Inhibitors in the My Life, Our Future Research Repository.

Journal: Frontiers in medicine

Published: March 24, 2022

A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs.

A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs.

Journal: The Journal of biological chemistry

Published: April 06, 2020

Showing 1-12 of 25

Last Updated: 09/26/2026