Sandeep K. Talapatra

29/39 Brunswick Square
London, ENG WC1N1AX, United Kingdom

Last Updated: 09/26/2026

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Found 15 publications

Tetrazole-containing naphthalene bis-sulfonamide Keap1-Nrf2 interaction inhibitors with unexpected binding modes.

Tetrazole-containing naphthalene bis-sulfonamide Keap1-Nrf2 interaction inhibitors with unexpected binding modes.

Journal: Redox biology

Published: September 13, 2025

Phenyl Bis-Sulfonamide Keap1-Nrf2 Protein-Protein Interaction Inhibitors with an Alternative Binding Mode.

Phenyl Bis-Sulfonamide Keap1-Nrf2 Protein-Protein Interaction Inhibitors with an Alternative Binding Mode.

Journal: Journal of medicinal chemistry

Published: May 13, 2022

Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5-Inhibitor Complexes.

Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5-Inhibitor Complexes.

Journal: Molecular cancer therapeutics

Published: February 13, 2019

Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases.

Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases.

Journal: Biology open

Published: January 04, 2019

The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation.

The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation.

Journal: Journal of cell science

Published: December 04, 2018

Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids.

Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids.

Journal: Chembiochem : a European journal of chemical biology

Published: May 29, 2018

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.

Journal: European journal of medicinal chemistry

Published: April 10, 2018

The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.

The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.

Journal: Oncotarget

Published: July 05, 2017

Depsidones from Lichens as Natural Product Inhibitors of M-Phase Phosphoprotein 1, a Human Kinesin Required for Cytokinesis.

Depsidones from Lichens as Natural Product Inhibitors of M-Phase Phosphoprotein 1, a Human Kinesin Required for Cytokinesis.

Journal: Journal of natural products

Published: June 15, 2016

New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.

New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.

Journal: Bioorganic & medicinal chemistry

Published: October 22, 2015

The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.

The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.

Journal: eLife

Published: January 14, 2015

Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism.

Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism.

Journal: Journal of medicinal chemistry

Published: July 24, 2013

Showing 1-12 of 15

Last Updated: 09/26/2026