Sanford J. Shattil

Hematology

200 W Arbor Dr
San Diego, CA 92103

Last Updated: 09/26/2026

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Found 28 publications

Talin, a Rap1 effector for integrin activation at the plasma membrane, also promotes Rap1 activity by disrupting sequestration of Rap1 by SHANK3.

Talin, a Rap1 effector for integrin activation at the plasma membrane, also promotes Rap1 activity by disrupting sequestration of Rap1 by SHANK3.

Journal: Journal of cell science

Published: October 08, 2024

Cancer-Associated Venous Thromboembolic Disease, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.

Cancer-Associated Venous Thromboembolic Disease, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN

Published: October 19, 2021

Platelet SHARPIN regulates platelet adhesion and inflammatory responses through associations with αIIbβ3 and LUBAC.

Platelet SHARPIN regulates platelet adhesion and inflammatory responses through associations with αIIbβ3 and LUBAC.

Journal: Blood advances

Published: June 24, 2021

Optogenetics-based localization of talin to the plasma membrane promotes activation of β3 integrins.

Optogenetics-based localization of talin to the plasma membrane promotes activation of β3 integrins.

Journal: The Journal of biological chemistry

Published: January 21, 2021

Genetic Instruction of Megakaryocytes and Platelets Derived from Human Induced Pluripotent Stem Cells for Studies of Integrin Regulation.

Genetic Instruction of Megakaryocytes and Platelets Derived from Human Induced Pluripotent Stem Cells for Studies of Integrin Regulation.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: November 20, 2020

Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.

Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.

Journal: Nucleic acid therapeutics

Published: February 12, 2020

SHARPIN at the nexus of integrin, immune, and inflammatory signaling in human platelets.

SHARPIN at the nexus of integrin, immune, and inflammatory signaling in human platelets.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 26, 2019

NCCN Guidelines Insights: Cancer-Associated Venous Thromboembolic Disease, Version 2.2018.

NCCN Guidelines Insights: Cancer-Associated Venous Thromboembolic Disease, Version 2.2018.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN

Published: November 17, 2018

uPAR isoform 2 forms a dimer and induces severe kidney disease in mice.

uPAR isoform 2 forms a dimer and induces severe kidney disease in mice.

Journal: The Journal of clinical investigation

Published: September 10, 2018

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.

Journal: Blood advances

Published: May 01, 2018

Optogenetic interrogation of integrin αVβ3 function in endothelial cells.

Optogenetic interrogation of integrin αVβ3 function in endothelial cells.

Journal: Journal of cell science

Published: April 19, 2017

Integrin-based therapeutics: biological basis, clinical use and new drugs.

Integrin-based therapeutics: biological basis, clinical use and new drugs.

Journal: Nature reviews. Drug discovery

Published: January 30, 2016

Showing 1-12 of 28

Last Updated: 09/26/2026