Sang Lee-Kook

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 55 publications

Protection of skin from UVB-induced photoaging: Antioxidant and anti-inflammatory effects of avenanthramide C from oat sprout extract via suppression of MAPK pathways.

Protection of skin from UVB-induced photoaging: Antioxidant and anti-inflammatory effects of avenanthramide C from oat sprout extract via suppression of MAPK pathways.

Journal: Journal of photochemistry and photobiology. B, Biology

Published: February 05, 2026

Anti-NSCLC efficacy of a novel ROR1/PI3Kα/BRD4 multi-target inhibitor.

Anti-NSCLC efficacy of a novel ROR1/PI3Kα/BRD4 multi-target inhibitor.

Journal: Bioorganic & medicinal chemistry

Published: September 05, 2025

Cumambrin A from Chrysanthemum boreale attenuates inflammation and oxidative stress through TRIF-dependent signaling inhibition and Nrf2/HO-1 pathway activation.

Cumambrin A from Chrysanthemum boreale attenuates inflammation and oxidative stress through TRIF-dependent signaling inhibition and Nrf2/HO-1 pathway activation.

Journal: Journal of ethnopharmacology

Published: August 29, 2025

Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer.

Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer.

Journal: eLife

Published: April 17, 2025

Design, synthesis and evaluation of acetylcholine-antitumor lipid hybrids led to identification of a potential anticancer agent disrupting the CDK4/6-Rb pathway in lung cancer.

Design, synthesis and evaluation of acetylcholine-antitumor lipid hybrids led to identification of a potential anticancer agent disrupting the CDK4/6-Rb pathway in lung cancer.

Journal: RSC medicinal chemistry

Published: December 18, 2024

Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells.

Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells.

Journal: Biochemical pharmacology

Published: November 05, 2024

Antitumor activity of selenopsammaplin A analog (SPA-10091-HCl) via histone methyltransferase DOT1L degradation and apoptosis induction in castration-resistant prostate cancer cells.

Antitumor activity of selenopsammaplin A analog (SPA-10091-HCl) via histone methyltransferase DOT1L degradation and apoptosis induction in castration-resistant prostate cancer cells.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: November 01, 2024

Buddlejasaponin IV inhibits proliferation and migration via STAT3 suppression in gefitinib-resistant non-small cell lung cancer cells.

Buddlejasaponin IV inhibits proliferation and migration via STAT3 suppression in gefitinib-resistant non-small cell lung cancer cells.

Journal: BMC complementary medicine and therapies

Published: October 16, 2024

Discovery of a stilbenoid-flavanone hybrid as an antitumor Wnt/β-catenin signaling pathway inhibitor.

Discovery of a stilbenoid-flavanone hybrid as an antitumor Wnt/β-catenin signaling pathway inhibitor.

Journal: Bioorganic chemistry

Published: August 28, 2023

Scaffold hopping of N-benzyl-3,4,5-trimethoxyaniline: 5,6,7-Trimethoxyflavan derivatives as novel potential anticancer agents modulating hippo signaling pathway.

Scaffold hopping of N-benzyl-3,4,5-trimethoxyaniline: 5,6,7-Trimethoxyflavan derivatives as novel potential anticancer agents modulating hippo signaling pathway.

Journal: European journal of medicinal chemistry

Published: March 13, 2023

Synthesis and biological evaluation of atropisomeric tetrahydroisoquinolines overcoming docetaxel resistance in triple-negative human breast cancer cells.

Synthesis and biological evaluation of atropisomeric tetrahydroisoquinolines overcoming docetaxel resistance in triple-negative human breast cancer cells.

Journal: Bioorganic chemistry

Published: February 23, 2023

Novel lignans from Zanthoxylum nitidum and antiproliferation activity of sesaminone in osimertinib-resistant non-small cell lung cancer cells.

Novel lignans from Zanthoxylum nitidum and antiproliferation activity of sesaminone in osimertinib-resistant non-small cell lung cancer cells.

Journal: Bioorganic chemistry

Published: September 14, 2022

Showing 1-12 of 55

Last Updated: 09/26/2026