Sara I. Liin
Linkoeping, E 58185, Sweden
Last Updated: 09/26/2026
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Found 47 publications
Discovery of Small-Molecule Inhibitors of the KCNQ1/Kv7.1 Potassium Channel with Virtual Screening and Functional Validation in Electrophysiological Assays and KCNQ1-Knockout Neural Stem Cells.
Journal: ACS chemical neuroscience
Published: May 21, 2026
Synthetic cannabinoid receptor agonists inhibit the cardiac voltage-gated potassium channel hERG.
Journal: Acta pharmacologica Sinica
Published: January 11, 2026
In vitro γ-aminobutyric acid A (GABAA) receptor activity and binding interactions at the α+/γ2- interface of 53 prescription and designer benzodiazepines.
Journal: Communications chemistry
Published: December 18, 2025
Early neurological symptoms and epilepsy outcomes in individuals with the recurrent GABRG2 p.(Ala106Thr) gain-of-function variant: Structural and phenotypic insights.
Journal: Epilepsia
Published: October 11, 2025
Two-step voltage-sensor activation of the human KV7.4 channel and effect of a deafness-associated mutation.
Journal: Nature communications
Published: August 20, 2025
Cannabidiol inhibits both human KV7.1 and KV7.1/KCNE1 channels through distinct sites.
Journal: Acta pharmacologica Sinica
Published: July 07, 2025
Beneficial action potential duration-shortening effects, but deleterious negative inotropism of IKs-activator docosahexaenoyl glycine in long QT syndrome type 2.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Published: April 10, 2025
Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent.
Journal: Experimental physiology
Published: December 18, 2024
The endocannabinoid ARA-S facilitates the activation of cardiac Kv7.1/KCNE1 channels from different species.
Journal: Channels (Austin, Tex.)
Published: October 27, 2024
Rescue of loss-of-function long QT syndrome-associated mutations in KV7.1/KCNE1 by the endocannabinoid N-arachidonoyl-L-serine (ARA-S).
Journal: British journal of pharmacology
Published: July 17, 2024
Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism.
Journal: Nature structural & molecular biology
Published: September 22, 2023
Last Updated: 09/26/2026