Sara M. Lopes

Coimbra, 3004504, Portugal

Last Updated: 09/26/2026

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Found 15 publications

Ketogenic diet as a therapeutic strategy for neurodegenerative diseases: from mechanisms to translational challenges.

Ketogenic diet as a therapeutic strategy for neurodegenerative diseases: from mechanisms to translational challenges.

Journal: Translational neurodegeneration

Published: October 23, 2025

Extracellular vesicles-mediated delivery of SpCas9 RNPs for therapeutic gene editing in Spinocerebellar Ataxia Type 3.

Extracellular vesicles-mediated delivery of SpCas9 RNPs for therapeutic gene editing in Spinocerebellar Ataxia Type 3.

Journal: Biomaterials

Published: August 01, 2025

Circadian rhythms are disrupted in patients and preclinical models of Machado-Joseph disease.

Circadian rhythms are disrupted in patients and preclinical models of Machado-Joseph disease.

Journal: Brain : a journal of neurology

Published: January 03, 2025

Extracellular vesicles-associated AAVs for the treatment of Machado-Joseph disease.

Extracellular vesicles-associated AAVs for the treatment of Machado-Joseph disease.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: October 03, 2024

Regional distribution of polymorphisms associated to the disease-causing gene of spinocerebellar ataxia type 3.

Regional distribution of polymorphisms associated to the disease-causing gene of spinocerebellar ataxia type 3.

Journal: Journal of neurology

Published: September 05, 2024

Isolation of Adeno-associated Viral Vectors Through a Single-step and Semi-automated Heparin Affinity Chromatography Protocol.

Isolation of Adeno-associated Viral Vectors Through a Single-step and Semi-automated Heparin Affinity Chromatography Protocol.

Journal: Journal of visualized experiments : JoVE

Published: April 22, 2024

Exploring the potential of cell-derived vesicles for transient delivery of gene editing payloads.

Exploring the potential of cell-derived vesicles for transient delivery of gene editing payloads.

Journal: Advanced drug delivery reviews

Published: December 10, 2023

Bridging the Gap between Field Experiments and Machine Learning: The EC H2020 B-GOOD Project as a Case Study towards Automated Predictive Health Monitoring of Honey Bee Colonies.

Bridging the Gap between Field Experiments and Machine Learning: The EC H2020 B-GOOD Project as a Case Study towards Automated Predictive Health Monitoring of Honey Bee Colonies.

Journal: Insects

Published: November 25, 2023

miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3.

miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3.

Journal: Nucleic acid therapeutics

Published: December 08, 2021

A new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification.

A new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification.

Journal: Gene therapy

Published: June 20, 2021

ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease.

ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: December 19, 2020

Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders.

Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders.

Journal: Brain : a journal of neurology

Published: February 07, 2019

Showing 1-12 of 15

Last Updated: 09/26/2026