Sarah E. Squire
Oxford, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 18 publications
Synthesis of aryl-fused bicyclo[3.1.1]heptanes and validation as naphthyl bioisosteres.
Journal: Nature chemistry
Published: November 26, 2024
Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy.
Journal: Bioorganic & medicinal chemistry
Published: April 04, 2022
IDEAL-D Framework for Device Innovation: A Consensus Statement on the Preclinical Stage.
Journal: Annals of surgery
Published: April 15, 2021
Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy.
Journal: European journal of medicinal chemistry
Published: December 01, 2020
Decreasing HepG2 Cytotoxicity by Lowering the Lipophilicity of Benzo[d]oxazolephosphinate Ester Utrophin Modulators.
Journal: ACS medicinal chemistry letters
Published: July 20, 2020
2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy.
Journal: Journal of medicinal chemistry
Published: June 20, 2020
From diagnosis to therapy in Duchenne muscular dystrophy.
Journal: Biochemical Society transactions
Published: April 22, 2020
Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid.
Journal: Angewandte Chemie (International ed. in English)
Published: September 27, 2019
The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy.
Journal: Human molecular genetics
Published: January 07, 2019
Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD.
Journal: Human molecular genetics
Published: August 14, 2018
Micro-utrophin Improves Cardiac and Skeletal Muscle Function of Severely Affected D2/mdx Mice.
Journal: Molecular therapy. Methods & clinical development
Published: July 20, 2018
Last Updated: 09/26/2026