Sarah Lilley

Brighton, ENG BN19QJ, United Kingdom

Last Updated: 09/26/2026

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Found 10 publications

Optimisation of a novel series of ENaC inhibitors, leading to the selection of the long-acting inhaled clinical candidate ETD001, a potential new treatment for cystic fibrosis.

Optimisation of a novel series of ENaC inhibitors, leading to the selection of the long-acting inhaled clinical candidate ETD001, a potential new treatment for cystic fibrosis.

Journal: European journal of medicinal chemistry

Published: August 15, 2024

The Tmem16a chloride channel is required for mucin maturation after secretion from goblet-like cells in the Xenopus tropicalis tadpole skin.

The Tmem16a chloride channel is required for mucin maturation after secretion from goblet-like cells in the Xenopus tropicalis tadpole skin.

Journal: Scientific reports

Published: February 26, 2024

ETD001: A novel inhaled ENaC blocker with an extended duration of action in vivo.

ETD001: A novel inhaled ENaC blocker with an extended duration of action in vivo.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Published: February 05, 2024

Niclosamide does not modulate airway epithelial function through blocking of the calcium activated chloride channel, TMEM16A.

Niclosamide does not modulate airway epithelial function through blocking of the calcium activated chloride channel, TMEM16A.

Journal: Frontiers in pharmacology

Published: January 11, 2023

Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction.

Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction.

Journal: FASEB bioAdvances

Published: May 11, 2020

TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis.

TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis.

Journal: American journal of respiratory and critical care medicine

Published: January 04, 2020

Protocol for a cluster randomised controlled trial evaluating a parenting with home visitation programme to prevent physical and emotional abuse of children in Indonesia: the Families First Programme.

Protocol for a cluster randomised controlled trial evaluating a parenting with home visitation programme to prevent physical and emotional abuse of children in Indonesia: the Families First Programme.

Journal: BMJ open

Published: February 21, 2019

Family structure and sexual and reproductive health outcomes among adolescents in rural Sierra Leone.

Family structure and sexual and reproductive health outcomes among adolescents in rural Sierra Leone.

Journal: Global public health

Published: April 17, 2015

Variomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation.

Variomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation.

Journal: The Journal of biological chemistry

Published: November 27, 2014

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 23, 2013

Showing 1-10 of 10

Last Updated: 09/26/2026