Sarah L. Nickels

6, Avenue Du Swing
Belvaux, ES 4367, Luxembourg

Last Updated: 09/26/2026

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Found 20 publications

Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modeling.

Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modeling.

Journal: iScience

Published: May 16, 2025

Single-cell analysis reveals shared and distinct molecular signatures in brain organoid models of neurodegeneration and neuroinflammation.

Single-cell analysis reveals shared and distinct molecular signatures in brain organoid models of neurodegeneration and neuroinflammation.

Journal: Alzheimer's research & therapy

Published: January 27, 2025

The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degeneration.

The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degeneration.

Journal: Journal of neuroinflammation

Published: January 02, 2025

Highly scalable and standardized organ-on-chip platform with TEER for biological barrier modeling.

Highly scalable and standardized organ-on-chip platform with TEER for biological barrier modeling.

Journal: Tissue barriers

Published: February 12, 2024

Cystatin C Secretion in Blood Derivatives and Cellular Models of Idiopathic Parkinson's Disease.

Cystatin C Secretion in Blood Derivatives and Cellular Models of Idiopathic Parkinson's Disease.

Journal: Parkinson's disease

Published: October 19, 2023

Treating Parkinson's Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration.

Treating Parkinson's Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration.

Journal: Cells

Published: August 29, 2023

Omics data integration suggests a potential idiopathic Parkinson's disease signature.

Omics data integration suggests a potential idiopathic Parkinson's disease signature.

Journal: Communications biology

Published: June 30, 2023

Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.

Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.

Journal: NPJ Parkinson's disease

Published: January 12, 2023

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.

Journal: Glia

Published: January 21, 2022

Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.

Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.

Journal: American journal of human genetics

Published: June 14, 2021

Is serine racemase (SRR) a second hit target for LRRK2-G2019S induced Parkinson's disease?

Is serine racemase (SRR) a second hit target for LRRK2-G2019S induced Parkinson's disease?

Journal: Neural regeneration research

Published: September 28, 2020

Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson's disease.

Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson's disease.

Journal: Stem cell research

Published: April 08, 2020

Showing 1-12 of 20

Last Updated: 09/26/2026