Sarah Schemmert

Juelich, NW, Germany

Last Updated: 09/26/2026

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Found 23 publications

Pharmacokinetic properties of the clinical drug candidate PRI-002 with regard to genotype, sex, age, dose-dependence and food effects in mice.

Pharmacokinetic properties of the clinical drug candidate PRI-002 with regard to genotype, sex, age, dose-dependence and food effects in mice.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: July 03, 2026

In-depth characterization of the CaV2.2-knockout mouse line.

In-depth characterization of the CaV2.2-knockout mouse line.

Journal: Scientific reports

Published: April 27, 2026

Elucidation of the influence of the CaV2.2 calcium channel on ALS disease progression in the SOD1*G93A mouse model.

Elucidation of the influence of the CaV2.2 calcium channel on ALS disease progression in the SOD1*G93A mouse model.

Journal: Neurobiology of disease

Published: January 08, 2026

Disruption of ClC-3-mediated 2Cl-/H+ exchange leads to behavioural deficits and thalamic atrophy.

Disruption of ClC-3-mediated 2Cl-/H+ exchange leads to behavioural deficits and thalamic atrophy.

Journal: Scientific reports

Published: March 28, 2025

Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.

Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.

Journal: Nature neuroscience

Published: June 18, 2023

Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs - A model of sporadic Alzheimer's disease.

Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs - A model of sporadic Alzheimer's disease.

Journal: Heliyon

Published: January 24, 2023

Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies.

Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies.

Journal: International journal of molecular sciences

Published: November 24, 2022

Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo.

Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo.

Journal: Cell reports. Medicine

Published: December 08, 2021

Structural basis for the inhibition of IAPP fibril formation by the co-chaperonin prefoldin.

Structural basis for the inhibition of IAPP fibril formation by the co-chaperonin prefoldin.

Journal: Nature communications

Published: October 14, 2021

Sex-Related Motor Deficits in the Tau-P301L Mouse Model.

Sex-Related Motor Deficits in the Tau-P301L Mouse Model.

Journal: Biomedicines

Published: July 29, 2021

PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer's Disease.

PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer's Disease.

Journal: International journal of molecular sciences

Published: May 31, 2021

In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer's Disease.

In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer's Disease.

Journal: International journal of molecular sciences

Published: May 21, 2021

Showing 1-12 of 23

Last Updated: 09/26/2026