Sarah V. Holt

Glossop Rd
Sheffield, ENG S102JF, United Kingdom

Last Updated: 09/26/2026

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Found 8 publications

Independent Head-to-Head Comparison of Commercial Artificial Intelligence Devices for Lung Cancer Detection on Chest Radiographs.

Independent Head-to-Head Comparison of Commercial Artificial Intelligence Devices for Lung Cancer Detection on Chest Radiographs.

Journal: Radiology

Published: May 19, 2026

Evaluating the performance of artificial intelligence software for lung nodule detection on chest radiographs in a retrospective real-world UK population.

Evaluating the performance of artificial intelligence software for lung nodule detection on chest radiographs in a retrospective real-world UK population.

Journal: BMJ open

Published: November 08, 2023

Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.

Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.

Journal: mAbs

Published: September 04, 2020

Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.

Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 04, 2020

A pharmacokinetic-pharmacodynamic model predicting tumour growth inhibition after intermittent administration with the mTOR kinase inhibitor AZD8055.

A pharmacokinetic-pharmacodynamic model predicting tumour growth inhibition after intermittent administration with the mTOR kinase inhibitor AZD8055.

Journal: British journal of pharmacology

Published: October 07, 2016

Identification of selective inhibitors of RET and comparison with current clinical candidates through development and validation of a robust screening cascade.

Identification of selective inhibitors of RET and comparison with current clinical candidates through development and validation of a robust screening cascade.

Journal: F1000Research

Published: July 19, 2016

The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.

The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.

Journal: European journal of medicinal chemistry

Published: August 27, 2015

Enhanced apoptosis and tumor growth suppression elicited by combination of MEK (selumetinib) and mTOR kinase inhibitors (AZD8055).

Enhanced apoptosis and tumor growth suppression elicited by combination of MEK (selumetinib) and mTOR kinase inhibitors (AZD8055).

Journal: Cancer research

Published: January 25, 2012

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Last Updated: 09/26/2026