Saskia M. Burm

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 20 publications

Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects.

Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects.

Journal: Journal for immunotherapy of cancer

Published: March 24, 2025

DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.

DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.

Journal: Journal for immunotherapy of cancer

Published: April 26, 2022

Mechanistic and pharmacodynamic studies of DuoBody-CD3x5T4 in preclinical tumor models.

Mechanistic and pharmacodynamic studies of DuoBody-CD3x5T4 in preclinical tumor models.

Journal: Life science alliance

Published: April 13, 2022

An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation.

An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation.

Journal: Oncoimmunology

Published: February 21, 2022

Systematic study of tissue factor expression in solid tumors.

Systematic study of tissue factor expression in solid tumors.

Journal: Cancer reports (Hoboken, N.J.)

Published: January 07, 2022

Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.

Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.

Journal: Cancer discovery

Published: October 18, 2021

Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia-derived cues for maintenance of microglia identity.

Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia-derived cues for maintenance of microglia identity.

Journal: Glia

Published: June 23, 2021

Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program.

Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program.

Journal: Brain, behavior, & immunity - health

Published: April 22, 2021

Tissue-specific features of microglial innate immune responses.

Tissue-specific features of microglial innate immune responses.

Journal: Neurochemistry international

Published: September 02, 2020

Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson's disease.

Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson's disease.

Journal: Acta neuropathologica communications

Published: March 29, 2019

An Overview of in vitro Methods to Study Microglia.

An Overview of in vitro Methods to Study Microglia.

Journal: Frontiers in cellular neuroscience

Published: May 30, 2018

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.

Journal: Glia

Published: May 18, 2018

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Last Updated: 09/26/2026