Saskia Schlossarek

Hamburg, HH, Germany

Last Updated: 09/26/2026

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Found 36 publications

Perinatal death in pig models of hypertrophic cardiomyopathy carrying sarcomere pathogenic variants.

Perinatal death in pig models of hypertrophic cardiomyopathy carrying sarcomere pathogenic variants.

Journal: Journal of molecular and cellular cardiology plus

Published: March 11, 2025

Chronic Activation of Tubulin Tyrosination Improves Heart Function.

Chronic Activation of Tubulin Tyrosination Improves Heart Function.

Journal: Circulation research

Published: September 16, 2024

Mavacamten shows broad benefit in human and mouse models of MYBPC3-related hypertrophic cardiomyopathy.

Mavacamten shows broad benefit in human and mouse models of MYBPC3-related hypertrophic cardiomyopathy.

Journal: Nature cardiovascular research

Published: March 22, 2024

Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy.

Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy.

Journal: Journal of molecular and cellular cardiology plus

Published: November 03, 2023

Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy.

Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy.

Journal: Journal of molecular and cellular cardiology plus

Published: August 15, 2023

EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy.

EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy.

Journal: Circulation research

Published: July 21, 2023

Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function.

Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function.

Journal: bioRxiv : the preprint server for biology

Published: June 09, 2023

ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes.

ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes.

Journal: Cells

Published: August 09, 2022

Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy.

Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy.

Journal: EMBO molecular medicine

Published: June 08, 2022

CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes.

CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes.

Journal: The FEBS journal

Published: June 23, 2021

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.

Journal: Circulation. Heart failure

Published: January 12, 2021

A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway.

A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway.

Journal: Autophagy

Published: November 30, 2020

Showing 1-12 of 36

Last Updated: 09/26/2026