Satoshi Obika

Suita, Japan

Last Updated: 09/26/2026

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Found 189 publications

Effect of sugar modifications on the solution stability of nucleoside phosphoramidites.

Effect of sugar modifications on the solution stability of nucleoside phosphoramidites.

Journal: Nucleosides, nucleotides & nucleic acids

Published: August 29, 2026

An improved guanidine protecting group for the efficient synthesis of GuNA[t-Bu]-modified antisense oligonucleotides.

An improved guanidine protecting group for the efficient synthesis of GuNA[t-Bu]-modified antisense oligonucleotides.

Journal: Organic & biomolecular chemistry

Published: June 18, 2026

Amidation of Phosphonoacetate-Modified Oligonucleotides and Evaluation of the Properties of the Synthesized Oligonucleotides.

Amidation of Phosphonoacetate-Modified Oligonucleotides and Evaluation of the Properties of the Synthesized Oligonucleotides.

Journal: Organic letters

Published: April 16, 2026

BNANC clamp PCR for simple and sensitive detection of KRAS and EGFR mutations.

BNANC clamp PCR for simple and sensitive detection of KRAS and EGFR mutations.

Journal: Bioorganic & medicinal chemistry

Published: February 25, 2026

Effects of N-1-Mer Impurities in Antisense Oligonucleotides on the Target RNA Suppression.

Effects of N-1-Mer Impurities in Antisense Oligonucleotides on the Target RNA Suppression.

Journal: Nucleic acid therapeutics

Published: February 04, 2026

Development of ARL4C antisense oligonucleotide with reduced off-target effects and enhanced efficacy as an anti-cancer drug.

Development of ARL4C antisense oligonucleotide with reduced off-target effects and enhanced efficacy as an anti-cancer drug.

Journal: In vitro cellular & developmental biology. Animal

Published: December 14, 2025

Sequence-dependent RNA cleavage by the 8-17 DNAzyme: Identification of preferred tetranucleotide motifs.

Sequence-dependent RNA cleavage by the 8-17 DNAzyme: Identification of preferred tetranucleotide motifs.

Journal: Bioorganic & medicinal chemistry

Published: November 05, 2025

Genetic Encoding of a Trifunctional Photo-Cross-Linker with a Cleavable Alkyl Ester Moiety.

Genetic Encoding of a Trifunctional Photo-Cross-Linker with a Cleavable Alkyl Ester Moiety.

Journal: Chembiochem : a European journal of chemical biology

Published: October 30, 2025

Development of Synthetic Routes to 2'-O,4'-C-Spirocyclopentylene-Bridged Nucleic Acids: Thymidine, Guanosine, and Adenosine.

Development of Synthetic Routes to 2'-O,4'-C-Spirocyclopentylene-Bridged Nucleic Acids: Thymidine, Guanosine, and Adenosine.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: September 29, 2025

Current trends in liquid chromatography-mass spectrometry analysis of small interfering RNAs: A short review.

Current trends in liquid chromatography-mass spectrometry analysis of small interfering RNAs: A short review.

Journal: Journal of chromatography. A

Published: August 31, 2025

Cycloalkane Incorporation Into the 2',4'-Bridge of Locked Nucleic Acid: Enhancing Nuclease Stability, Reducing Phosphorothioate Modifications, and Lowering Hepatotoxicity in Antisense Oligonucleotides.

Cycloalkane Incorporation Into the 2',4'-Bridge of Locked Nucleic Acid: Enhancing Nuclease Stability, Reducing Phosphorothioate Modifications, and Lowering Hepatotoxicity in Antisense Oligonucleotides.

Journal: JACS Au

Published: August 08, 2025

Phthalimide: a potential warhead for switchable and bioorthogonal conjugation.

Phthalimide: a potential warhead for switchable and bioorthogonal conjugation.

Journal: Chemical communications (Cambridge, England)

Published: August 06, 2025

Showing 1-12 of 189

Last Updated: 09/26/2026