Saul C. Costa

Coimbra, 3000548, Portugal

Last Updated: 09/26/2026

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Found 12 publications

New Promising Steroidal Aromatase Inhibitors with Multi-Target Action on Estrogen and Androgen Receptors for Breast Cancer Treatment.

New Promising Steroidal Aromatase Inhibitors with Multi-Target Action on Estrogen and Androgen Receptors for Breast Cancer Treatment.

Journal: Cancers

Published: November 27, 2024

Plant-derived and dietary phenolic cinnamic acid derivatives: Anti-inflammatory properties.

Plant-derived and dietary phenolic cinnamic acid derivatives: Anti-inflammatory properties.

Journal: Food chemistry

Published: April 17, 2024

Steroidal epoxides as anticancer agents in lung, prostate and breast cancers: The case of 1,2-epoxysteroids.

Steroidal epoxides as anticancer agents in lung, prostate and breast cancers: The case of 1,2-epoxysteroids.

Journal: Biochemical pharmacology

Published: January 24, 2024

Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids.

Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids.

Journal: Bioorganic chemistry

Published: September 23, 2022

Design, synthesis, and antitumor activity evaluation of steroidal oximes.

Design, synthesis, and antitumor activity evaluation of steroidal oximes.

Journal: Bioorganic & medicinal chemistry

Published: June 24, 2021

Effects of new C6-substituted steroidal aromatase inhibitors in hormone-sensitive breast cancer cells: Cell death mechanisms and modulation of estrogen and androgen receptors.

Effects of new C6-substituted steroidal aromatase inhibitors in hormone-sensitive breast cancer cells: Cell death mechanisms and modulation of estrogen and androgen receptors.

Journal: The Journal of steroid biochemistry and molecular biology

Published: July 25, 2019

C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships.

C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships.

Journal: Journal of medicinal chemistry

Published: March 12, 2019

Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells.

Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology

Published: October 28, 2016

Exploring new chemical functionalities to improve aromatase inhibition of steroids.

Exploring new chemical functionalities to improve aromatase inhibition of steroids.

Journal: Bioorganic & medicinal chemistry

Published: March 01, 2016

Plant derived and dietary phenolic antioxidants: anticancer properties.

Plant derived and dietary phenolic antioxidants: anticancer properties.

Journal: Food chemistry

Published: December 02, 2014

Development, optimization and application of an analytical methodology by ultra performance liquid chromatography-tandem mass spectrometry for determination of amanitins in urine and liver samples.

Development, optimization and application of an analytical methodology by ultra performance liquid chromatography-tandem mass spectrometry for determination of amanitins in urine and liver samples.

Journal: Analytica chimica acta

Published: July 06, 2013

Design, synthesis and biochemical studies of new 7α-allylandrostanes as aromatase inhibitors.

Design, synthesis and biochemical studies of new 7α-allylandrostanes as aromatase inhibitors.

Journal: Steroids

Published: December 14, 2012

Showing 1-12 of 12

Last Updated: 09/26/2026