Last Updated: 09/26/2026
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Found 31 publications
Discovery of Biased Dual-Agonists of Glucagon-Like Peptide 1 and Glucagon Receptors through Mutation of a Conserved Aspartate.
Journal: ACS medicinal chemistry letters
Published: November 10, 2025
Antibody-Drug Conjugates of NLRP3 Agonists: How Overcoming Lysosomal Accumulation Necessitated Noncanonical Linker Attachments.
Journal: Journal of medicinal chemistry
Published: April 29, 2025
Design and Optimization of Selectivity-Tunable Toll-like Receptor 7/8 Agonists as Novel Antibody-Drug Conjugate Payloads.
Journal: Journal of medicinal chemistry
Published: August 22, 2024
Author Correction: Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Journal: Nature communications
Published: January 23, 2024
Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants.
Journal: Scientific reports
Published: April 19, 2023
Discovery of Insulin Receptor Partial Agonists MK-5160 and MK-1092 as Novel Basal Insulins with Potential to Improve Therapeutic Index.
Journal: Journal of medicinal chemistry
Published: March 17, 2022
Hexamerization of Anti-SARS CoV IgG1 Antibodies Improves Neutralization Capacity.
Journal: Frontiers in immunology
Published: January 28, 2022
Leveraging nonstructural data to predict structures and affinities of protein-ligand complexes.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: October 15, 2021
Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Journal: Nature communications
Published: September 02, 2021
Delineating the Ligand-Receptor Interactions That Lead to Biased Signaling at the μ-Opioid Receptor.
Delineating the Ligand-Receptor Interactions That Lead to Biased Signaling at the μ-Opioid Receptor.
Journal: Journal of chemical information and modeling
Published: July 12, 2021
Small molecule agonists of toll-like receptors 7 and 8: a patent review 2014 - 2020.
Journal: Expert opinion on therapeutic patents
Published: October 14, 2020
Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation.
Journal: Nature communications
Published: July 30, 2020
Last Updated: 09/26/2026