Sean G. Rudd
Stockholm, AB 17164, Sweden
Last Updated: 09/26/2026
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Found 36 publications
Antisense Dipeptide Repeat Proteins Drive Widescale Purine Metabolism Aberration in C9orf72 Amyotrophic Lateral Sclerosis via ADA.
Journal: International journal of molecular sciences
Published: January 25, 2026
Targeting IMPDH to inhibit SAMHD1 in KMT2A-rearranged leukaemia.
Journal: Cell cycle (Georgetown, Tex.)
Published: December 16, 2025
Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity.
Journal: The Journal of biological chemistry
Published: October 26, 2025
Uridine cytidine kinases govern molnupiravir bioactivation and anti-SARS-CoV-2 activity.
Journal: PLoS pathogens
Published: October 23, 2025
Repurposing Asparaginase Therapy to Target Cisplatin-Resistant Cancer Cells.
Journal: Fundamental & clinical pharmacology
Published: June 18, 2025
Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP-Lyase Function.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
Published: January 29, 2025
Understanding the interplay between dNTP metabolism and genome stability in cancer.
Journal: Disease models & mechanisms
Published: August 29, 2024
The N-terminal SAM domain of the dNTPase SAMHD1 is not required for inhibition by small molecule TH6342.
Journal: Nucleosides, nucleotides & nucleic acids
Published: June 03, 2024
Targeting pan-essential pathways in cancer with cytotoxic chemotherapy: challenges and opportunities.
Journal: Cancer chemotherapy and pharmacology
Published: February 06, 2023
Last Updated: 09/26/2026