Sean M. Fortier

Sean M. Fortier

Pulmonary Medicine

1500 E Medical Center Dr
Floor 3 Reception C
Ann Arbor, MI 48109

Last Updated: 09/26/2026

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Found 13 publications

Longitudinal Single-Cell RNA-seq Profiling of Lung Cell Phenotypes, Signaling, and Cross-talk During Fibrosis Resolution.

Longitudinal Single-Cell RNA-seq Profiling of Lung Cell Phenotypes, Signaling, and Cross-talk During Fibrosis Resolution.

Journal: bioRxiv : the preprint server for biology

Published: April 17, 2026

MRC2-mediated collagen internalization is reduced in fibrotic lung fibroblasts and increased upon phenotypic dedifferentiation.

MRC2-mediated collagen internalization is reduced in fibrotic lung fibroblasts and increased upon phenotypic dedifferentiation.

Journal: JCI insight

Published: October 31, 2025

Mechanistic basis for the antifibrotic actions of cAMP-based therapies.

Mechanistic basis for the antifibrotic actions of cAMP-based therapies.

Journal: European respiratory review : an official journal of the European Respiratory Society

Published: October 22, 2025

Targeting Plasminogen Activator Inhibitor-1 with a Novel Small Molecule Inhibitor Attenuates Lung Fibrosis.

Targeting Plasminogen Activator Inhibitor-1 with a Novel Small Molecule Inhibitor Attenuates Lung Fibrosis.

Journal: Research square

Published: September 02, 2025

Reimagining Fibrosis Research, Outcomes, and Therapeutics Through the Lens of Resolution.

Reimagining Fibrosis Research, Outcomes, and Therapeutics Through the Lens of Resolution.

Journal: Seminars in respiratory and critical care medicine

Published: August 19, 2025

Morphological reprogramming of primary cilia length mitigates the fibrotic phenotype in fibroblasts across diverse fibrotic conditions.

Morphological reprogramming of primary cilia length mitigates the fibrotic phenotype in fibroblasts across diverse fibrotic conditions.

Journal: Journal of cell science

Published: June 04, 2025

Distinct cAMP regulation in scleroderma lung and skin myofibroblasts governs their dedifferentiation via p38α inhibition.

Distinct cAMP regulation in scleroderma lung and skin myofibroblasts governs their dedifferentiation via p38α inhibition.

Journal: bioRxiv : the preprint server for biology

Published: March 10, 2025

MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution.

MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution.

Journal: The Journal of clinical investigation

Published: July 05, 2023

KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis.

KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis.

Journal: JCI insight

Published: April 01, 2022

Illuminating the lung regenerative potential of prostanoids.

Illuminating the lung regenerative potential of prostanoids.

Journal: Science advances

Published: March 23, 2022

Myofibroblast dedifferentiation proceeds via distinct transcriptomic and phenotypic transitions.

Myofibroblast dedifferentiation proceeds via distinct transcriptomic and phenotypic transitions.

Journal: JCI insight

Published: October 07, 2020

Mechanical Stretch: An Important and Understudied Feature of Acute and Chronic Lung Injury.

Mechanical Stretch: An Important and Understudied Feature of Acute and Chronic Lung Injury.

Journal: American journal of respiratory and critical care medicine

Published: March 04, 2020

Showing 1-12 of 13

Last Updated: 09/26/2026