Sebastiaan T. Sassen

Rotterdam, ZH, Netherlands

Last Updated: 09/26/2026

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Found 42 publications

Beyond Traditional Covariates: An Interpretable Machine Learning Workflow for Improved Hybrid Pharmacometric Modeling.

Beyond Traditional Covariates: An Interpretable Machine Learning Workflow for Improved Hybrid Pharmacometric Modeling.

Journal: CPT: pharmacometrics & systems pharmacology

Published: February 19, 2026

Differences in antihypertensive drug blood levels in patients with hypertension (DECISION): a prospective study comparing pharmacokinetics and pharmacodynamics of perindopril in younger and older patients.

Differences in antihypertensive drug blood levels in patients with hypertension (DECISION): a prospective study comparing pharmacokinetics and pharmacodynamics of perindopril in younger and older patients.

Journal: Blood pressure

Published: October 24, 2025

The magnitude of the pharmacodynamic index for NOSO-502: pathogen clearance, emergence of resistance and human dose predictions.

The magnitude of the pharmacodynamic index for NOSO-502: pathogen clearance, emergence of resistance and human dose predictions.

Journal: The Journal of antimicrobial chemotherapy

Published: October 06, 2025

Population pharmacokinetics of amikacin in patients with a haematological disorder: A prospective, observational study.

Population pharmacokinetics of amikacin in patients with a haematological disorder: A prospective, observational study.

Journal: The Journal of infection

Published: July 25, 2025

The pharmacodynamics of polymyxin B in Acinetobacter baumannii in murine thigh and lung infection models.

The pharmacodynamics of polymyxin B in Acinetobacter baumannii in murine thigh and lung infection models.

Journal: The Journal of antimicrobial chemotherapy

Published: July 20, 2025

A Population Pharmacokinetic Model and Dosing Algorithm to Guide the Tacrolimus Starting and Follow-Up Dose in Living and Deceased Donor Kidney Transplant Recipients.

A Population Pharmacokinetic Model and Dosing Algorithm to Guide the Tacrolimus Starting and Follow-Up Dose in Living and Deceased Donor Kidney Transplant Recipients.

Journal: Clinical pharmacokinetics

Published: May 18, 2025

A Clinical Pharmacological Perspective on Intraperitoneal Chemotherapy.

A Clinical Pharmacological Perspective on Intraperitoneal Chemotherapy.

Journal: Drugs

Published: April 23, 2025

Inadequate imipenem dosing in patients with decreased kidney function: a global clinical pharmacokinetic study.

Inadequate imipenem dosing in patients with decreased kidney function: a global clinical pharmacokinetic study.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Published: February 09, 2025

Drug release from docetaxel-entrapped core-crosslinked polymeric micelles: A population pharmacokinetic modelling approach based on clinical data.

Drug release from docetaxel-entrapped core-crosslinked polymeric micelles: A population pharmacokinetic modelling approach based on clinical data.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: January 27, 2025

If it does not help, it might hurt: Pharmacodynamics of a second IVIg course in Guillain-Barré syndrome.

If it does not help, it might hurt: Pharmacodynamics of a second IVIg course in Guillain-Barré syndrome.

Journal: Annals of clinical and translational neurology

Published: December 24, 2024

Selecting the Best Pharmacokinetic Models for a Priori Model-Informed Precision Dosing with Model Ensembling.

Selecting the Best Pharmacokinetic Models for a Priori Model-Informed Precision Dosing with Model Ensembling.

Journal: Clinical pharmacokinetics

Published: September 06, 2024

Pharmacodynamics of NOSO-502 studied in vitro and in vivo: determination of the dominant pharmacodynamic index driver.

Pharmacodynamics of NOSO-502 studied in vitro and in vivo: determination of the dominant pharmacodynamic index driver.

Journal: The Journal of antimicrobial chemotherapy

Published: August 20, 2024

Showing 1-12 of 42

Last Updated: 09/26/2026