Sebastian B. Jorgensen

Malov, 2760, Denmark

Last Updated: 09/26/2026

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Found 25 publications

A loss-of-function variant in GFRAL associates with increased alcohol consumption in humans.

A loss-of-function variant in GFRAL associates with increased alcohol consumption in humans.

Journal: bioRxiv : the preprint server for biology
Published: April 10, 2026

GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling.

GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling.

Journal: Cell metabolism
Published: December 11, 2025

A GDF-15-GFRAL axis controls autoimmune T cell responses during neuroinflammation.

A GDF-15-GFRAL axis controls autoimmune T cell responses during neuroinflammation.

Journal: Nature immunology
Published: March 09, 2025

Deletion of GFRAL blunts weight lowering effects of FGF21 in female mice.

Deletion of GFRAL blunts weight lowering effects of FGF21 in female mice.

Journal: The Journal of endocrinology
Published: January 20, 2025

Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy.

Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy.

Journal: Cell reports
Published: March 25, 2024

Circulating and hepatic levels of growth differentiation factor 15 in patients with metabolic dysfunction-associated steatotic liver disease.

Circulating and hepatic levels of growth differentiation factor 15 in patients with metabolic dysfunction-associated steatotic liver disease.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology
Published: January 11, 2024

GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism.

GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism.

Journal: Cell metabolism
Published: December 12, 2022

GDF15 promotes weight loss by enhancing energy expenditure in muscle.

GDF15 promotes weight loss by enhancing energy expenditure in muscle.

Journal: Nature
Published: July 21, 2022

Central regulation of the anorexigenic receptor GFRAL.

Central regulation of the anorexigenic receptor GFRAL.

Journal: Nature metabolism
Published: February 18, 2022

Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals.

Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals.

Journal: American journal of physiology. Endocrinology and metabolism
Published: August 09, 2021

Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.

Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 30, 2021

GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease.

GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease.

Journal: Nature reviews. Endocrinology
Published: June 17, 2021
Showing 1-12 of 25

Last Updated: 09/26/2026