Sebastian Polak

John Street
Sheffield, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 100 publications

Relating plaque psoriasis barrier function changes with the underlying skin morphology and physiology.

Relating plaque psoriasis barrier function changes with the underlying skin morphology and physiology.

Journal: Journal of pharmaceutical sciences

Published: March 11, 2026

Exploring Tafamidis Effects Through PBPK-QSP Modelling.

Exploring Tafamidis Effects Through PBPK-QSP Modelling.

Journal: Pharmaceutics

Published: January 29, 2026

Insight into human allogeneic CAR-T therapy: an open-access dataset.

Insight into human allogeneic CAR-T therapy: an open-access dataset.

Journal: Drug discovery today

Published: January 22, 2026

Development and Implementation of a Hinderance-based In Vitro Model for Porous Membranes.

Development and Implementation of a Hinderance-based In Vitro Model for Porous Membranes.

Journal: The AAPS journal

Published: January 16, 2026

Dataset of xenobiotics human renal clearance values.

Dataset of xenobiotics human renal clearance values.

Journal: Database : the journal of biological databases and curation

Published: December 21, 2025

Mechanistic dermal patch modelling for fentanyl: Linking in vitro release and permeation data to a physiologically based pharmacokinetic approach.

Mechanistic dermal patch modelling for fentanyl: Linking in vitro release and permeation data to a physiologically based pharmacokinetic approach.

Journal: Journal of pharmaceutical sciences

Published: December 12, 2025

Virtual Bioequivalence Assessment of Long-acting Injectable Suspensions Using PBPK Modeling: Part 1. Impact of particle Size on Formulation Variability.

Virtual Bioequivalence Assessment of Long-acting Injectable Suspensions Using PBPK Modeling: Part 1. Impact of particle Size on Formulation Variability.

Journal: The AAPS journal

Published: October 29, 2025

Phenomenological model of transthyretin stabilization.

Phenomenological model of transthyretin stabilization.

Journal: Scientific reports

Published: October 13, 2025

Evaluating the Impact of Intestinal Bile Salts on Drug Absorption Using PBPK Modeling: Case Studies With Efavirenz, Cinnarizine, and Posaconazole.

Evaluating the Impact of Intestinal Bile Salts on Drug Absorption Using PBPK Modeling: Case Studies With Efavirenz, Cinnarizine, and Posaconazole.

Journal: CPT: pharmacometrics & systems pharmacology

Published: August 19, 2025

Demonstration of in vitro-in vivo relationship (IVIVR) and virtual bioequivalence (VBE) between progesterone intravaginal rings using physiologically based pharmacokinetic (PBPK) modelling.

Demonstration of in vitro-in vivo relationship (IVIVR) and virtual bioequivalence (VBE) between progesterone intravaginal rings using physiologically based pharmacokinetic (PBPK) modelling.

Journal: Journal of pharmaceutical sciences

Published: June 22, 2025

Use of PBPK modelling to extrapolate in vitro porcine ear skin permeability to in vivo human dermal absorption.

Use of PBPK modelling to extrapolate in vitro porcine ear skin permeability to in vivo human dermal absorption.

Journal: International journal of pharmaceutics

Published: May 15, 2025

Physiologically based pharmacokinetic modelling of in vitro skin permeation of sunscreen actives under various experimental conditions.

Physiologically based pharmacokinetic modelling of in vitro skin permeation of sunscreen actives under various experimental conditions.

Journal: International journal of pharmaceutics

Published: April 24, 2025

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Last Updated: 09/26/2026