Sebastien Combes

Marseille, France

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 20 publications

Correction: Conditional generation of free radicals by selective activation of alkoxyamines: towards more effective and less toxic targeting of brain tumors.

Correction: Conditional generation of free radicals by selective activation of alkoxyamines: towards more effective and less toxic targeting of brain tumors.

Journal: Chemical science

Published: June 10, 2026

Engineering SIRPα conformational plasticity to reveal a cryptic pocket suitable for structure-based drug design.

Engineering SIRPα conformational plasticity to reveal a cryptic pocket suitable for structure-based drug design.

Journal: bioRxiv : the preprint server for biology

Published: January 07, 2026

Alkyne modification of DNA cross-linking antitumor agent SJG-136 to monitor induced lesions in cells by click chemistry.

Alkyne modification of DNA cross-linking antitumor agent SJG-136 to monitor induced lesions in cells by click chemistry.

Journal: Chemico-biological interactions

Published: June 25, 2025

Conditional generation of free radicals by selective activation of alkoxyamines: towards more effective and less toxic targeting of brain tumors.

Conditional generation of free radicals by selective activation of alkoxyamines: towards more effective and less toxic targeting of brain tumors.

Journal: Chemical science

Published: March 10, 2023

A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells.

A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells.

Journal: Nucleic acids research

Published: November 25, 2022

From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia.

From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia.

Journal: Nature communications

Published: September 22, 2022

CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation.

CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation.

Journal: Journal of medicinal chemistry

Published: March 29, 2022

Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.

Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.

Journal: European journal of medicinal chemistry

Published: June 01, 2020

Allocolchicinoids bearing a Michael acceptor fragment for possible irreversible binding of tubulin.

Allocolchicinoids bearing a Michael acceptor fragment for possible irreversible binding of tubulin.

Journal: RSC medicinal chemistry

Published: February 22, 2020

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach.

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach.

Journal: Journal of medicinal chemistry

Published: June 09, 2018

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.

Journal: Nature communications

Published: February 01, 2017

Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery.

Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery.

Journal: ACS chemical biology

Published: May 25, 2016

Showing 1-12 of 20

Last Updated: 09/26/2026