Seiichi Nagano

Suita, 5650871, Japan

Last Updated: 09/26/2026

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Found 32 publications

Single-nucleus multiome shows motor neuron glutamate overactivation in amyotrophic lateral sclerosis.

Single-nucleus multiome shows motor neuron glutamate overactivation in amyotrophic lateral sclerosis.

Journal: Brain : a journal of neurology

Published: March 01, 2025

Conformational Switch in the Alpha-Synuclein C-Terminal Domain Directs Its Fibril Polymorphs.

Conformational Switch in the Alpha-Synuclein C-Terminal Domain Directs Its Fibril Polymorphs.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: February 19, 2025

TDP-43 transports ferritin heavy chain mRNA to regulate oxidative stress in neuronal axons.

TDP-43 transports ferritin heavy chain mRNA to regulate oxidative stress in neuronal axons.

Journal: Neurochemistry international

Published: October 23, 2024

Accelerated senescence exacerbates α-synucleinopathy in senescence-accelerated prone 8 mice via persistent neuroinflammation.

Accelerated senescence exacerbates α-synucleinopathy in senescence-accelerated prone 8 mice via persistent neuroinflammation.

Journal: Neurochemistry international

Published: September 29, 2024

Lysophagy protects against propagation of α-synuclein aggregation through ruptured lysosomal vesicles.

Lysophagy protects against propagation of α-synuclein aggregation through ruptured lysosomal vesicles.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 26, 2023

RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS.

RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS.

Journal: Science advances

Published: November 22, 2023

Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD.

Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD.

Journal: Acta neuropathologica communications

Published: September 01, 2023

Crosstalk between Oxidative Stress and Aging in Neurodegeneration Disorders.

Crosstalk between Oxidative Stress and Aging in Neurodegeneration Disorders.

Journal: Cells

Published: January 11, 2023

Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism.

Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism.

Journal: Acta neuropathologica

Published: October 04, 2022

An Exploratory Trial of EPI-589 in Amyotrophic Lateral Sclerosis (EPIC-ALS): Protocol for a Multicenter, Open-Labeled, 24-Week, Single-Group Study.

An Exploratory Trial of EPI-589 in Amyotrophic Lateral Sclerosis (EPIC-ALS): Protocol for a Multicenter, Open-Labeled, 24-Week, Single-Group Study.

Journal: JMIR research protocols

Published: August 24, 2022

Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice.

Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice.

Journal: Molecular therapy. Nucleic acids

Published: April 22, 2022

MDMX elevation by a novel Mdmx-p53 interaction inhibitor mitigates neuronal damage after ischemic stroke.

MDMX elevation by a novel Mdmx-p53 interaction inhibitor mitigates neuronal damage after ischemic stroke.

Journal: Scientific reports

Published: April 12, 2022

Showing 1-12 of 32

Last Updated: 09/26/2026