Semi Lim
Incheon, Republic of Korea
Last Updated: 09/26/2026
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Found 15 publications
Allosteric Inhibition of the Tumor-Promoting Interaction Between Exon 2-Depleted Splice Variant of Aminoacyl-Transfer RNA Synthetase-Interacting Multifunctional Protein 2 and Heat Shock Protein 70.
Journal: The Journal of pharmacology and experimental therapeutics
Published: May 27, 2021
AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.
Journal: Nature communications
Published: May 18, 2021
Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2.
Journal: Molecules (Basel, Switzerland)
Published: May 15, 2020
An Isoform of the Oncogenic Splice Variant AIMP2-DX2 Detected by a Novel Monoclonal Antibody.
Journal: Biomolecules
Published: May 08, 2020
Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy.
Journal: Journal of medicinal chemistry
Published: April 22, 2020
2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment.
Journal: Journal of medicinal chemistry
Published: March 27, 2020
ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation.
Journal: Experimental & molecular medicine
Published: April 08, 2019
Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Journal: Nature chemical biology
Published: March 04, 2019
Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization.
Journal: Molecular nutrition & food research
Published: December 08, 2015
PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine.
Journal: PloS one
Published: June 02, 2015
Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways.
Journal: The Journal of biological chemistry
Published: April 29, 2015
Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission.
Journal: The Journal of biological chemistry
Published: July 09, 2013
Last Updated: 09/26/2026