Sena M. Pinheiro

Rio De Janeiro, RJ 21941913, Brazil

Last Updated: 09/26/2026

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Found 14 publications

Multitarget Strategy for Treatment of Pulmonary Arterial Hypertension: Combination of Mesenchymal Cells with Novel PDE-4 Inhibitor.

Multitarget Strategy for Treatment of Pulmonary Arterial Hypertension: Combination of Mesenchymal Cells with Novel PDE-4 Inhibitor.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: November 26, 2025

Design, Synthesis, and Biological Evaluation of Novel Triazine-Based Dual Histone Deacetylase/phosphatidylinositol 3-kinase Inhibitors for Breast Cancer Therapy.

Design, Synthesis, and Biological Evaluation of Novel Triazine-Based Dual Histone Deacetylase/phosphatidylinositol 3-kinase Inhibitors for Breast Cancer Therapy.

Journal: ChemMedChem

Published: November 17, 2025

Discovery of N‑Acylhydrazone Derivatives as ROCK Inhibitors: A Journey from Virtual Screening and Structure-Based De Novo Design to the Identification of ROCK2 Selective Inhibitors and Beyond.

Discovery of N‑Acylhydrazone Derivatives as ROCK Inhibitors: A Journey from Virtual Screening and Structure-Based De Novo Design to the Identification of ROCK2 Selective Inhibitors and Beyond.

Journal: ACS bio & med chem Au

Published: November 11, 2025

Histone Deacetylases in Neurodegenerative Diseases and Their Potential Role as Therapeutic Targets: Shedding Light on Astrocytes.

Histone Deacetylases in Neurodegenerative Diseases and Their Potential Role as Therapeutic Targets: Shedding Light on Astrocytes.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: August 19, 2025

HDACs in the Brain: From Chromatin Remodeling to Neurodegenerative Disease.

HDACs in the Brain: From Chromatin Remodeling to Neurodegenerative Disease.

Journal: Cells

Published: July 24, 2025

Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease.

Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: May 11, 2025

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups.

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 16, 2025

Regioselective Nucleophilic Aromatic Substitution: Theoretical and Experimental Insights into 4-Aminoquinazoline Synthesis as a Privileged Structure in Medicinal Chemistry.

Regioselective Nucleophilic Aromatic Substitution: Theoretical and Experimental Insights into 4-Aminoquinazoline Synthesis as a Privileged Structure in Medicinal Chemistry.

Journal: Molecules (Basel, Switzerland)

Published: November 17, 2024

Remapping the Chemical Space and the Pharmacological Space of Drugs: What Can We Expect from the Road Ahead?

Remapping the Chemical Space and the Pharmacological Space of Drugs: What Can We Expect from the Road Ahead?

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 31, 2024

The Magic Methyl and Its Tricks in Drug Discovery and Development.

The Magic Methyl and Its Tricks in Drug Discovery and Development.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: July 19, 2023

Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative.

Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: October 11, 2018

N-Acylhydrazones as drugs.

N-Acylhydrazones as drugs.

Journal: Bioorganic & medicinal chemistry letters

Published: May 12, 2018

Showing 1-12 of 14

Last Updated: 09/26/2026