Senthilvelrajan Kaniyappan

Bonn, NW, Germany

Last Updated: 09/26/2026

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Found 21 publications

Recapitulation of plaque formation, tau pathology, and neurodegeneration in a human 3D matrix model of Alzheimer's disease.

Recapitulation of plaque formation, tau pathology, and neurodegeneration in a human 3D matrix model of Alzheimer's disease.

Journal: Cell reports methods

Published: April 29, 2025

Discovery of Orally Available and Brain Penetrant AEP Inhibitors.

Discovery of Orally Available and Brain Penetrant AEP Inhibitors.

Journal: Journal of medicinal chemistry

Published: December 13, 2023

Spreading of Tau Protein Does Not Depend on Aggregation Propensity.

Spreading of Tau Protein Does Not Depend on Aggregation Propensity.

Journal: Journal of molecular neuroscience : MN

Published: May 26, 2023

Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy.

Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy.

Journal: International journal of molecular sciences

Published: March 16, 2023

Microfluidic Chamber Technology to Study Missorting and Spreading of Tau Protein in Alzheimer's Disease.

Microfluidic Chamber Technology to Study Missorting and Spreading of Tau Protein in Alzheimer's Disease.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: October 31, 2022

A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro.

A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro.

Journal: Alzheimer's research & therapy

Published: October 31, 2021

Potent Tau Aggregation Inhibitor D-Peptides Selected against Tau-Repeat 2 Using Mirror Image Phage Display.

Potent Tau Aggregation Inhibitor D-Peptides Selected against Tau-Repeat 2 Using Mirror Image Phage Display.

Journal: Chembiochem : a European journal of chemical biology

Published: June 14, 2021

Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates.

Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates.

Journal: The EMBO journal

Published: June 08, 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Journal: Autophagy

Published: February 26, 2021

A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications.

A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications.

Journal: The Journal of biological chemistry

Published: September 02, 2020

Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes.

Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes.

Journal: Alzheimer's & dementia (New York, N. Y.)

Published: August 27, 2020

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments.

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments.

Journal: Molecular neurodegeneration

Published: April 07, 2020

Showing 1-12 of 21

Last Updated: 09/26/2026