Seo-hyeon Bae

Gyeonggi-do, Republic of Korea

Last Updated: 09/26/2026

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Found 25 publications

Molecular Dynamics-Guided Sterol Engineering of mRNA-Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen-Selective Immunity.

Molecular Dynamics-Guided Sterol Engineering of mRNA-Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen-Selective Immunity.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: March 27, 2026

Nonclinical safety evaluation strategies for mRNA/LNPs platform agents: Evidence from comprehensive animal toxicity studies.

Nonclinical safety evaluation strategies for mRNA/LNPs platform agents: Evidence from comprehensive animal toxicity studies.

Journal: Toxicology letters

Published: March 24, 2026

Optimized Lipid Nanoparticles with Tail-Modified Ionizable Lipids for Safer mRNA Delivery.

Optimized Lipid Nanoparticles with Tail-Modified Ionizable Lipids for Safer mRNA Delivery.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: March 04, 2026

Erratum: Rational design and applications of piperazine and cyclohexane ionizable lipids for PKU and SSADH deficiency.

Erratum: Rational design and applications of piperazine and cyclohexane ionizable lipids for PKU and SSADH deficiency.

Journal: Molecular therapy. Nucleic acids

Published: December 30, 2025

A novel mRNA-based multi-cytokine strategy to reprogram the peritoneal tumor microenvironment in ovarian cancer.

A novel mRNA-based multi-cytokine strategy to reprogram the peritoneal tumor microenvironment in ovarian cancer.

Journal: Journal of nanobiotechnology

Published: August 14, 2025

Integration of TLR7/8 agonists into lipid nanoparticles enhances antigen-specific immune responses to N1-methyl-Ψ-modified mRNA-LNP vaccines.

Integration of TLR7/8 agonists into lipid nanoparticles enhances antigen-specific immune responses to N1-methyl-Ψ-modified mRNA-LNP vaccines.

Journal: Journal of biological engineering

Published: July 04, 2025

ApoE deficiency protects from mRNA vaccine-induced mitochondrial dysfunction at the injection site under metabolic stress.

ApoE deficiency protects from mRNA vaccine-induced mitochondrial dysfunction at the injection site under metabolic stress.

Journal: Theranostics

Published: June 13, 2025

Comparative immunologic profiling of mRNA and protein-conjugated vaccines: acute inflammatory responses and anti-PEG antibody production.

Comparative immunologic profiling of mRNA and protein-conjugated vaccines: acute inflammatory responses and anti-PEG antibody production.

Journal: Animal cells and systems

Published: June 12, 2025

A systemic evaluation of the effect of dsRNA contamination on mRNA vaccine expression and immunogenicity.

A systemic evaluation of the effect of dsRNA contamination on mRNA vaccine expression and immunogenicity.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: June 04, 2025

Rapid-Turnaround Co-Administration of mRNA-Based MHC-I and MHC-II-Restricted Neoantigens Enhances Immune Responses of Antigen-Specific CD8+ T Cells and Anti-Cancer Efficacy in Colorectal Cancer.

Rapid-Turnaround Co-Administration of mRNA-Based MHC-I and MHC-II-Restricted Neoantigens Enhances Immune Responses of Antigen-Specific CD8+ T Cells and Anti-Cancer Efficacy in Colorectal Cancer.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: April 09, 2025

Effective mRNA-based therapy using E7 antigen and IL-12 cytokine in head and neck cancer mice models.

Effective mRNA-based therapy using E7 antigen and IL-12 cytokine in head and neck cancer mice models.

Journal: Vaccine

Published: March 31, 2025

Loop structure in poly(A) tail of mRNA vaccine enhances antigen translation efficiency and mRNA stability.

Loop structure in poly(A) tail of mRNA vaccine enhances antigen translation efficiency and mRNA stability.

Journal: NPJ vaccines

Published: February 26, 2025

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Last Updated: 09/26/2026