Seonadh M. O'leary

St James's Hospital
Dublin, L, Ireland

Last Updated: 09/26/2026

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Found 18 publications

HIV inhibits Warburg metabolism in human macrophages infected with Mycobacterium tuberculosis.

HIV inhibits Warburg metabolism in human macrophages infected with Mycobacterium tuberculosis.

Journal: Scientific reports

Published: December 12, 2025

Mycobacterium tuberculosis Induces Warburg Metabolism in Human Alveolar Macrophages: A Transcriptomic Analysis.

Mycobacterium tuberculosis Induces Warburg Metabolism in Human Alveolar Macrophages: A Transcriptomic Analysis.

Journal: American journal of respiratory cell and molecular biology

Published: May 01, 2025

A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.

A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.

Journal: The Journal of clinical investigation

Published: May 31, 2022

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis.

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis.

Journal: Journal of visualized experiments : JoVE

Published: August 30, 2021

Tuberculosis lymph node granulomas: using transcriptomics to discover immunopathology paradigms and guide host-directed therapy.

Tuberculosis lymph node granulomas: using transcriptomics to discover immunopathology paradigms and guide host-directed therapy.

Journal: The Journal of clinical investigation

Published: August 02, 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Journal: Autophagy

Published: February 26, 2021

Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis.

Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis.

Journal: Frontiers in immunology

Published: February 03, 2021

Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis.

Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis.

Journal: Frontiers in immunology

Published: January 17, 2020

Selective effects of radiotherapy on viability and function of invariant natural killer T cells in vitro.

Selective effects of radiotherapy on viability and function of invariant natural killer T cells in vitro.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Published: September 16, 2019

Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21.

Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21.

Journal: Cell reports

Published: April 24, 2019

Cigarette Smoking Impairs the Bioenergetic Immune Response to Mycobacterium tuberculosis Infection.

Cigarette Smoking Impairs the Bioenergetic Immune Response to Mycobacterium tuberculosis Infection.

Journal: American journal of respiratory cell and molecular biology

Published: June 27, 2018

Inhalable poly(lactic-co-glycolic acid) (PLGA) microparticles encapsulating all-trans-Retinoic acid (ATRA) as a host-directed, adjunctive treatment for Mycobacterium tuberculosis infection.

Inhalable poly(lactic-co-glycolic acid) (PLGA) microparticles encapsulating all-trans-Retinoic acid (ATRA) as a host-directed, adjunctive treatment for Mycobacterium tuberculosis infection.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: April 23, 2018

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Last Updated: 09/26/2026