Serdar Durdagi

Istanbul, Turkey

Last Updated: 09/26/2026

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Found 165 publications

New 3H-1,2-Dithiole-3-thione derivatives: Design and synthesis, H2S-release profile, in vitro anticancer activity, and in silico multi-target assessment.

New 3H-1,2-Dithiole-3-thione derivatives: Design and synthesis, H2S-release profile, in vitro anticancer activity, and in silico multi-target assessment.

Journal: Molecular diversity

Published: May 01, 2026

Machine-learning-guided library screening and drug resistance profiling of HIV-1 protease inhibitors.

Machine-learning-guided library screening and drug resistance profiling of HIV-1 protease inhibitors.

Journal: Journal of molecular graphics & modelling

Published: March 30, 2026

Novel 1,2,3-Thiadiazole-based Hydrazone and 1,3,4-Oxadiazole hybrids as promising agents against Streptococcus mutans: Synthesis, biological evaluation, and molecular modeling studies.

Novel 1,2,3-Thiadiazole-based Hydrazone and 1,3,4-Oxadiazole hybrids as promising agents against Streptococcus mutans: Synthesis, biological evaluation, and molecular modeling studies.

Journal: Bioorganic chemistry

Published: March 17, 2026

Corrigendum to "Novel VARS1 variants define new clinical and molecular subtypes of a rare neurodevelopmental syndrome" [Biochim. Biophys. Acta Mol. Basis Dis. 1872 (2026)/168184].

Corrigendum to "Novel VARS1 variants define new clinical and molecular subtypes of a rare neurodevelopmental syndrome" [Biochim. Biophys. Acta Mol. Basis Dis. 1872 (2026)/168184].

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: March 12, 2026

Triazole-substituted pyrazole-pyrimidine hybrids as anticancer agents: synthesis, cytotoxicity, apoptosis mechanisms, and JAB1-targeted structure-based design.

Triazole-substituted pyrazole-pyrimidine hybrids as anticancer agents: synthesis, cytotoxicity, apoptosis mechanisms, and JAB1-targeted structure-based design.

Journal: Bioorganic chemistry

Published: December 15, 2025

Computational discovery and preclinical validation of a novel nanodrug eEF2 kinase inhibitor for suppression of tumor growth in triple-negative breast cancer by induction of ferroptosis and apoptosis.

Computational discovery and preclinical validation of a novel nanodrug eEF2 kinase inhibitor for suppression of tumor growth in triple-negative breast cancer by induction of ferroptosis and apoptosis.

Journal: International journal of biological macromolecules

Published: November 10, 2025

Novel VARS1 variants define new clinical and molecular subtypes of a rare neurodevelopmental syndrome.

Novel VARS1 variants define new clinical and molecular subtypes of a rare neurodevelopmental syndrome.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: October 07, 2025

Novel VARS1 variants define new clinical and molecular subtypes of a rare neurodevelopmental syndrome.

Novel VARS1 variants define new clinical and molecular subtypes of a rare neurodevelopmental syndrome.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: October 07, 2025

Niraparib Demonstrates Therapeutic Potential in Multiple Sclerosis through Inhibition of IL-17A Receptor Interaction and Promotion of Remyelination.

Niraparib Demonstrates Therapeutic Potential in Multiple Sclerosis through Inhibition of IL-17A Receptor Interaction and Promotion of Remyelination.

Journal: ACS chemical neuroscience

Published: September 09, 2025

Mathematical Modeling of Aβ-42 Dimerization Dynamics: Integrating Physics-Based Simulations, Graph-Based Variational Autoencoder-Driven Neural Relational Inference, and Chaos Theory.

Mathematical Modeling of Aβ-42 Dimerization Dynamics: Integrating Physics-Based Simulations, Graph-Based Variational Autoencoder-Driven Neural Relational Inference, and Chaos Theory.

Journal: ACS chemical neuroscience

Published: September 02, 2025

Advancing Accurate Quantification of Protein-Ligand Interactions: Differential Scanning Calorimetry as a Precision Screening Tool Using BCL-2 as a Model System.

Advancing Accurate Quantification of Protein-Ligand Interactions: Differential Scanning Calorimetry as a Precision Screening Tool Using BCL-2 as a Model System.

Journal: ChemMedChem

Published: August 31, 2025

Structure-activity modeling and hybrid machine learning-based prediction of bioactivity in pyrazole derivatives for drug discovery applications.

Structure-activity modeling and hybrid machine learning-based prediction of bioactivity in pyrazole derivatives for drug discovery applications.

Journal: Turkish journal of biology = Turk biyoloji dergisi

Published: August 05, 2025

Showing 1-12 of 165

Last Updated: 09/26/2026